Nisin infusion into surface cracks in oxide coatings to create an antibacterial metallic surface.

The efficacy of surface topology and chemistry on the ability for a surface to retain antimicrobial performance via the immobilization of a peptide was evaluated. A nanosecond pulsed laser was used to create oxide films on Ti-6Al-4V and 304L stainless steel. The laser conditions employed created a mudflat cracked surface on titanium, but no cracks on the steel.