Background: Three-dimensional MR fingerprinting (3D-MRF) has been increasingly used to assess cartilage degeneration, particularly in the knee joint, by looking into multiple relaxation parameters. A comparable 3D-MRF approach can be adapted to assess cartilage degeneration for the hip joint, with changes to accommodate specific challenges of hip joint imaging.
Purpose: To demonstrate the feasibility and repeatability of 3D-MRF in the bilateral hip jointly we map proton density (PD), T, T, T, and ∆B in clinically feasible scan times.
Purpose: To implement and evaluate the feasibility of brain spin-lattice relaxation in the rotating frame (T1ρ) mapping using a novel optimized pulse sequence that incorporates weighted spin-lock acquisitions, enabling high-resolution three-dimensional (3D) mapping.
Methods: The optimized variable flip-angle framework, previously proposed for knee T1ρ mapping, was enhanced by integrating weighted spin-lock acquisitions. This strategic combination significantly boosts signal-to-noise ratio (SNR) while reducing data acquisition time, facilitating high-resolution 3D-T1ρ mapping of the brain.
Purpose: To compare the performance of a learned magnetization-prepared gradient echo (L-MPGRE) sequence against a commonly used sequence for 3D T and T mapping of the knee joint, the magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (MAPSS), on bi-exponential (BE), stretched-exponential (SE), and mono-exponential (ME) relaxation models.
Methods: We used a combined differentiable and non-differentiable optimization to learn pulse sequence structure and its parameters for 3D T and T mapping of the knee joint using ME, SE, and BE models. The learned pulse sequence framework was used to improve quantitative accuracy and SNR and to reduce filtering effects.
Low-field strength scanners present an opportunity for more inclusive imaging exams and bring several challenges including lower signal-to-noise ratio (SNR) and longer scan times. Magnetic resonance fingerprinting (MRF) is a rapid quantitative multiparametric method that can enable multiple quantitative maps simultaneously. To demonstrate the feasibility of an MRF sequence for knee cartilage evaluation in a 0.
View Article and Find Full Text PDFMagnetic resonance imaging (MRI) stands as a vital medical imaging technique, renowned for its ability to offer high-resolution images of the human body with remarkable soft-tissue contrast. This enables healthcare professionals to gain valuable insights into various aspects of the human body, including morphology, structural integrity, and physiological processes. Quantitative imaging provides compositional measurements of the human body, but, currently, either it takes a long scan time or is limited to low spatial resolutions.
View Article and Find Full Text PDFBackground: Three-dimensional MR fingerprinting (3D-MRF) techniques have been recently described for simultaneous multiparametric mapping of knee cartilage. However, investigation of repeatability remains limited.
Purpose: To assess the intra-day and inter-day repeatabilities of knee cartilage T, T, and T maps using a 3D-MRF sequence for simultaneous measurement.
Magnetic Resonance Imaging (MRI) is an essential medical imaging modality that provides excellent soft-tissue contrast and high-resolution images of the human body, allowing us to understand detailed information on morphology, structural integrity, and physiologic processes. However, MRI exams usually require lengthy acquisition times. Methods such as parallel MRI and Compressive Sensing (CS) have significantly reduced the MRI acquisition time by acquiring less data through undersampling k-space.
View Article and Find Full Text PDFThe objective of the current study was to investigate age- and gender-related differences in lumbar intervertebral disk (IVD) strain with the use of static mechanical loading and continuous three-dimensional (3D) golden-angle radial sparse parallel (GRASP) MRI. A continuous 3D-GRASP stack-of-stars trajectory of the lumbar spine was performed on a 3-T scanner with static mechanical loading. Compressed sensing reconstruction, motion deformation maps, and Lagrangian strain maps during loading and recovery in the X-, Y-, and Z-directions were calculated for segmented IVD segments from L1/L2 to L5/S1.
View Article and Find Full Text PDFPurpose: To optimize the choice of the flip angles of magnetization-prepared gradient-echo sequences for improved accuracy, precision, and speed of 3D-T mapping.
Methods: We propose a new optimization approach for finding variable flip-angle values that improve magnetization-prepared gradient-echo sequences used for 3D-T mapping. This new approach can improve the accuracy and SNR, while reducing filtering effects.
Osteoarthritis (OA) is a widely occurring degenerative joint disease that is severely debilitating and causes significant socioeconomic burdens to society. Magnetic resonance imaging (MRI) is the preferred imaging modality for the morphological evaluation of cartilage due to its excellent soft tissue contrast and high spatial resolution. However, its utilization typically involves subjective qualitative assessment of cartilage.
View Article and Find Full Text PDFBioengineering (Basel)
February 2023
Magnetic Resonance Imaging (MRI) offers strong soft tissue contrast but suffers from long acquisition times and requires tedious annotation from radiologists. Traditionally, these challenges have been addressed separately with reconstruction and image analysis algorithms. To see if performance could be improved by treating both as end-to-end, we hosted the K2S challenge, in which challenge participants segmented knee bones and cartilage from 8× undersampled k-space.
View Article and Find Full Text PDFTwo optimization criteria based on Cramér-Rao Bounds are compared between each other and with non-optimized schedules for T mapping using synthetic data, model phantoms, and in-vivo knee cartilage. The curve fitting is done on complex-valued data using an iterative Nonlinear Least Squares (NLS) approach. The optimization criteria are compared based on the Mean Normalized Absolute Error (MNAE) and variance of the estimated parameters.
View Article and Find Full Text PDFIEEE Trans Ultrason Ferroelectr Freq Control
November 2021
Ultrasonic imaging is a common technique in nondestructive evaluation, as it presents advantages such as low cost and safety of operation. In many industries, the interior inspection of objects with complex geometry has become a necessity. This kind of inspection requires the transducer to be coupled to the object with the use of some technique, such as immersing the object in water.
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