J Proteome Res
December 2024
Breast cancer (BC) has become a global health problem, ranking first in incidence and fifth in mortality in women around the world. Although there are some diagnostic methods for the disease, these are not sufficiently effective and are invasive. In this work, we discriminated between patients without breast pathology (BP), with benign BP, and with BC based on the band patterns obtained from Western blot strip images of the autoantibody response to antigens of the T47D tumor line using and comparing supervised machine learning techniques to have a sensitive and accurate method.
View Article and Find Full Text PDFThe enhanced multi-objective symbolic discretization for time series () uses an evolutionary process to identify the appropriate discretization scheme in the Time Series Classification (TSC) task. It discretizes using a unique alphabet cut for each word segment. However, this kind of scheme has a higher computational cost.
View Article and Find Full Text PDFis a complex phenomenon that impacts human activities and the environment. For this reason, predicting its behavior is crucial to mitigating such effects. Deep learning techniques are emerging as a powerful tool for this task.
View Article and Find Full Text PDFGel zymography quantifies the activity of certain enzymes in tumor processes. These enzymes are widely used in medical diagnosis. In order to analyze them, experts classify the zymography spots into various classes according to their tonalities.
View Article and Find Full Text PDFObjective: To evaluate the association between body mass index (BMI) and performance of executive functions (EFs) in girls and boys with 9- and 10-year-old schoolchildren with moderate- to vigorous-intensity physical activity (MVPA) and sedentary behaviour.
Methods: A total of 120 schoolchildren (61 girls and 59 boys) were evaluated anthropometrically. The MVPA was evaluated with a self-report questionnaire.
The present study evaluated the effects of blackberry juice that is rich in different concentrations of anthocyanins and polyphenols (2.6 mg/kg anthocyanins, 14.57 mg/kg polyphenols; 5.
View Article and Find Full Text PDFBackground And Aim: the aim of the study was to use a validated questionnaire to identify factors associated with the development of gastric cancer (GC) in the Mexican population.
Methods: the study included cases and controls that were paired by sex and ± 10 years of age at diagnosis. In relation to cases, 46 patients with a confirmed histopathological diagnosis of adenocarcinoma-type GC, as reported in the hospital records, were selected, and 46 blood bank donors from the same hospital were included as controls.
Efforts have been being made to improve the diagnostic performance of colposcopy, trying to help better diagnose cervical cancer, particularly in developing countries. However, improvements in a number of areas are still necessary, such as the time it takes to process the full digital image of the cervix, the performance of the computing systems used to identify different kinds of tissues, and biopsy sampling. In this paper, we explore three different, well-known automatic classification methods (-Nearest Neighbors, Naïve Bayes, and C4.
View Article and Find Full Text PDFThe bias-variance dilemma is a well-known and important problem in Machine Learning. It basically relates the generalization capability (goodness of fit) of a learning method to its corresponding complexity. When we have enough data at hand, it is possible to use these data in such a way so as to minimize overfitting (the risk of selecting a complex model that generalizes poorly).
View Article and Find Full Text PDFIn this work, we present a novel application of time series discretization using evolutionary programming for the classification of precancerous cervical lesions. The approach optimizes the number of intervals in which the length and amplitude of the time series should be compressed, preserving the important information for classification purposes. Using evolutionary programming, the search for a good discretization scheme is guided by a cost function which considers three criteria: the entropy regarding the classification, the complexity measured as the number of different strings needed to represent the complete data set, and the compression rate assessed as the length of the discrete representation.
View Article and Find Full Text PDFBreast cancer is one of the leading causes of death among women worldwide. There are a number of techniques used for diagnosing this disease: mammography, ultrasound, and biopsy, among others. Each of these has well-known advantages and disadvantages.
View Article and Find Full Text PDFAfter Pap smear test, colposcopy is the most used technique to diagnose cervical cancer due to its higher sensitivity and specificity. One of the most promising approaches to improve the colposcopic test is the use of the aceto-white temporal patterns intrinsic to the color changes in digital images. However, there is not a complete understanding of how to use them to segment colposcopic images.
View Article and Find Full Text PDFWe evaluate the effectiveness of seven Bayesian network classifiers as potential tools for the diagnosis of breast cancer using two real-world databases containing fine-needle aspiration of the breast lesion cases collected by a single observer and multiple observers, respectively. The results show a certain ingredient of subjectivity implicitly contained in these data: we get an average accuracy of 93.04% for the former and 83.
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