Publications by authors named "Hector D Pardave-Alejandre"

Background: SARS-CoV-2 is a coronavirus described for the first time in China, in December 2019. This virus can cause a disease with a very variable spectrum that ranges from asymptomatic cases to deaths. The most severe cases are normally associated with comorbidities and with the age of the patient.

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Background: With the arrival of chikungunya (CHIKV) and zika (ZIKV) viruses in Mexico, there was a decrease in diagnosed dengue virus (DENV) cases. During the first years of cocirculation (2015-2017), the algorithms established by epidemiological surveillance systems and the installed capacity limited us to one diagnostic test per sample, so there was an underestimation of cases until September 2017, when a multiplex algorithm was implemented. Therefore, the objective of this study was determine the impact of the introduction of CHIKV and ZIKV on the incidence of diagnosed DENV in endemic areas of Mexico, when performing the rediagnosis, using the multiplex algorithm, in samples from the first three years of co-circulation of these arboviruses.

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Background: Enterovirus (EV) and herpes simplex virus 1 and 2 (HSV1 and HSV2) are the main etiologic agents of central nervous system infections. Early laboratory confirmation of these infections is performed by viral culture of the cerebrospinal fluid (CSF), or the detection of specific antibodies in serum (e.g.

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Article Synopsis
  • - Acute respiratory infections (ARIs) are a major global health issue, with around 80% of cases linked to unidentified viral agents, while influenza diagnostics are more prevalent and comprehensive.
  • - A study analyzed 872 throat swab samples for 14 non-influenza viruses using RT-qPCR, finding that 35.8% were positive, with rhinovirus, human respiratory syncytial virus, and human metapneumovirus being the most common; co-infections were also identified in 17.9% of cases.
  • - The findings highlight the importance of recognizing these non-influenza viruses year-round in Mexico, suggesting that improved testing could lead to better treatment strategies and reduced unnecessary antibiotic use, ultimately
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