Publications by authors named "Hector D Garcia-Verdugo"
Article Synopsis
- Nociceptive and pruriceptive neurons in the dorsal root ganglia send pain and itch signals to the spinal cord, with a small subset of these neurons specifically detecting itch-related stimuli like the cytokine IL-31.
- The study reveals that TMEM184B is crucial for the expression of itch receptors and that mice lacking this protein show diminished responses to IL-31 while still reacting normally to pain.
- TMEM184B's influence on pruriceptive neuron development occurs through Wnt signaling pathways, highlighting its role in establishing the diversity of sensations processed by the nervous system.
Understanding neuronal function at the local and circuit level requires understanding astrocyte function. We have provided a detailed analysis of astrocyte morphology and territory in the Drosophila third-instar ventral nerve cord where there already exists considerable understanding of the neuronal network. Astrocyte shape varies more than previously reported; many have bilaterally symmetrical partners, many have a high percentage of their arborization in adjacent segments, and many have branches that follow structural features.
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