Publications by authors named "Hector Aldaz"

A challenge in the structure-based design of specificity is modeling the negative states, i.e., the complexes that you do not want to form.

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Microtubules are hollow polymers of alphabeta-tubulin that show GTP-dependent assembly dynamics and comprise a critical part of the eukaryotic cytoskeleton. Initiation of new microtubules in vivo requires gamma-tubulin, organized as an oligomer within the 2.2-MDa gamma-tubulin ring complex (gamma-TuRC) of higher eukaryotes.

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