Publications by authors named "Heba Abu-Kaf"
Article Synopsis
- Gastrointestinal angiodysplasia (GIAD) is a rare condition, with an overall prevalence of 0.092%, primarily affecting older adults, particularly those aged 71-80, where the prevalence peaks at 0.37%.
- A study identified significant risk factors for GIAD, including liver cirrhosis, hypertension, and aortic stenosis, along with demographic factors like female gender, and noted that GIADs are less common in patients with malignancies.
- Understanding the associated clinical conditions and demographics of GIAD can aid in better recognizing its causes and developing effective treatment strategies for this rare gastrointestinal issue.
Article Synopsis
- Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease, and a study compared its impact between Arab and Jewish patients in Israel, analyzing data from over 200,000 individuals.
- Arab patients with NAFLD were diagnosed at a younger age and presented with higher rates of obesity, diabetes, and severe complications, such as cirrhosis and portal hypertension-related issues, compared to Jewish patients.
- Despite the higher complication rates, Arab patients demonstrated lower all-cause mortality and slightly higher liver transplantation rates, indicating the need for tailored prevention and treatment strategies based on ethnicity.
Background & Aims: Corticosteroids are the mainstay of treatment for hospitalized patients with acute severe ulcerative colitis (ASUC). However, whether the addition/continuation of mesalamine with corticosteroids during hospitalization is superior to corticosteroids alone is unknown.
Methods: This was a randomized controlled, investigator-blinded, clinical trial conducted in 10 centers in 7 countries.
Background: Patients with Crohn disease have debilitating psychological symptoms, mental fatigue, and poor quality of life. Psychological intervention may improve these symptoms.
Methods: We performed a randomized parallel-group physician-blinded trial of cognitive-behavioral and mindfulness-based stress reduction (COBMINDEX) on quality of life and psychological symptoms in adults with mild-moderate Crohn disease.
Adherence to treatment of chronic Hepatitis B Virus (HBV) is an important issue and can affect the complication rate. Nucleos(t)ide analogue as oral treatments are used for patients with necro-inflammatory activity and high viral load, with the goal of decline the complication rate such cirrhosis and hepatic cancer. We aimed to investigate the adherence to chronic HBV treatment.
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- The study examines the prevalence of NOD2/CARD15 mutations in Bedouin Arab patients with inflammatory bowel disease (IBD) and their relationship to disease characteristics.
- 68 IBD patients participated, with findings showing that Crohn's disease (CD) patients had a higher frequency of these mutations compared to those with ulcerative colitis (UC).
- Mutations carried were associated with younger age at diagnosis in CD patients, a male predominance among carriers, and older age in UC patients, highlighting genetic factors influencing IBD phenotypes in this population.
Objectives: Sepsis remains a disease with a high mortality rate. The study goal was to assess long-term survival of severe sepsis in young patients.
Design: Retrospective cohort study.