Publications by authors named "Heather Noble"

Article Synopsis
  • The study looked at how women in the UK with HIV managed their pregnancies, especially those who can keep their virus levels very low without treatment.
  • It compared pregnancies before and after 2012 when new guidelines changed how HIV was treated during pregnancy.
  • Even with the changes in treatment, there were no new cases of HIV passed to babies, and the way babies were delivered varied quite a bit in recent years.
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Background: Pre-exposure prophylaxis (PrEP) is highly effective and an important prevention tool for African adolescent girls and young women (AGYW), but adherence and persistence are challenging. PrEP adherence support strategies for African AGYW were studied in an implementation study.

Methods And Findings: HIV Prevention Trials Network (HPTN) 082 was conducted in Cape Town, Johannesburg (South Africa) and Harare (Zimbabwe) from October 2016 to October 2018 to evaluate PrEP uptake, persistence, and the effect of drug level feedback on adherence.

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Introduction: There are few data regarding the tolerability, safety, or efficacy of antenatal atazanavir. We report our clinical experience of atazanavir use in pregnancy.

Methods: A retrospective medical records review of atazanavir-exposed pregnancies in 12 London centres between 2004 and 2010.

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Background: Chronic subdural hematoma is a common presentation to the neurosurgical practice that tends to occur among the elderly.

Methods: We identify a rare occurrence of a chronic subdural hematoma in a young and otherwise healthy female patient who denied a traumatic brain injury.

Results: Upon reviewing the literature, we found only one reported case of a spontaneous nature in a young patient.

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Objectives: To document postpartum disease-free survival of HIV-infected women taking antiretroviral therapy (ART) during pregnancy.

Methods: Laboratory and clinical data were collected on all HIV-infected pregnant women delivering from 1998 to 2002 and followed up until September 2004 at 6 hospitals in London. Mothers were grouped according to receipt of zidovudine monotherapy (ZDVm), highly active antiretroviral therapy (HAART) given during and continued after pregnancy (cHAART), and short-term HAART given during pregnancy and discontinued on delivery (START).

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