Are children with Angelman syndrome at high risk for anesthetic complications?

Objectives/aims: To review seven children with Angelman syndrome (AS) undergoing 16 general anesthetics for both invasive and noninvasive procedures to determine if these children are at greater risk for anesthetic-related complications than the general population.

Background: Children with AS may exhibit unpredictable responses to GABA agonists because of abnormal GABA receptors. These abnormal receptors may affect AS patients' responses to sedation and general anesthesia.

Anonymous donation: a transplant center's experience.

As demands for organs increase, transplant centers are now considering alternative resources. This paper looks at the experiences of one kidney transplant center as it developed its anonymous donor protocol. The authors review the historical use of living donors and discuss why the program initially considered this type of donor.