Application of the Environmental Assessment Tool (EAT) as a process measure for a worksite weight management intervention.

Objective: To assess the ability of the Environmental Assessment Tool (EAT) to detect changes over time in workplace physical and social environmental supports for physical activity and nutrition; and predict employee engagement, behavior changes, and biometrics.

Methods: Analyses utilized site-level (n = 12) EAT scores. Differences-in-difference regressions tested changes in EAT scores over time across treatment sites.

Development of the Environmental Assessment Tool (EAT) to measure organizational physical and social support for worksite obesity prevention programs.

Objective: To describe the development, reliability, and validity of the Environmental Assessment Tool (EAT) for assessing worksite physical and social environmental support for obesity prevention.

Methods: The EAT was developed using a multistep process. Inter-rater reliability was estimated via Kappa and other measures.

Leptin resistance in mice is determined by gender and duration of exposure to high-fat diet.

Mice fed a high-fat diet are reported to be resistant to peripheral injections of leptin. We previously failed to induce leptin resistance in female mice fed a high-fat diet for 15 weeks. Therefore, we measured the responsiveness to peripheral infusions (10 microg/day) of leptin, and the responsiveness to third ventricle injections of leptin (1 microg) in male and female NIH Swiss mice fed low-fat (10% kcal) or high-fat (45% kcal) diets.