The interobserver reliability of pretest probability assessment in patients with suspected pulmonary embolism.

Introduction: Pretest probability assessment and objective testing are combined to appropriately manage patients with suspected pulmonary embolism (PE). However, the interobserver reliability of pretest probability assessment has not been investigated. We sought to determine (for patients with suspected PE) the interobserver reliability of pretest probability assessment (by overall impression (gestalt) versus an explicit clinical model).

A systematic review of the association between factor V Leiden or prothrombin gene variant and intrauterine growth restriction.

Objective: The purpose of this study was to conduct a systematic review of the literature of studies that examined the association between factor V Leiden and/or prothrombin gene variant and intrauterine growth restriction.

Study Design: This systematic review of studies assesses the association between factor V Leiden and/or prothrombin gene variant and intrauterine growth restriction.

Results: Ten case-control studies fulfilled the selection criteria for inclusion in the meta-analysis.