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Publications by authors named "Heather Anne N Ogana"

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Synopsis of recent research by authors named "Heather Anne N Ogana"

  • - Heather Anne N Ogana's research focuses on the development and optimization of antibody platforms, particularly utilizing heavy chain-only antibodies (HCAbs) and transgenic animals to advance therapeutic antibody discovery.
  • - One significant study highlights a multispecific antibody development platform based on HCAbs, showcasing their potential as versatile building blocks for antibody-based biologics due to their ability to tolerate fusions and construction without light chains.
  • - Another study introduces the OmniFlic transgenic rat model, which expresses a diverse repertoire of human antibodies with a fixed light chain, providing insights into heavy chain variability and monoclonal antibody characteristics for improved therapeutic applications.

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