Sugar-Lectin Interactions for Direct and Selective Detection of Bacteria Using QCM Biosensor.

Pathogenic () remains a safety concern in the preservation and quality of green leafy vegetables. Sugar-lectin interactions provide a reliable, specific, and effective sensing platform for the detection of bacteria as compared to the tedious conventional plate counting technique. Herein, we present the synthesis of 4-(N-mannosyl) benzoic acid (4-NMBA) and 4-thiophenyl-N-mannose (4-TNM) via a two-step reductive amination for the detection of using a quartz crystal microbalance (QCM) biosensor.