The mediating role of coping in the relationship between family function and resilience in adolescents and young adults who have a parent with lung cancer.

Purpose: Resilience plays an important role in helping individuals to adapt to adversity and improve their psychosocial outcomes. This study aims to examine the mediating role of coping in the relationship between family function and resilience in adolescents and young adults (AYAs) who have a parent with lung cancer.

Method: A total of 135 AYAs with a lung cancer parent were recruited from a tertiary grade A cancer center in southern China, and investigated using a self-designed general information questionnaire, the Resilience Scale for Chinese Adolescents, the Simplified Coping Style Questionnaire, and the Family Adaptation, Partnership, Growth, Affection, Resolve index.

Rhein lysinate decreases the generation of β-amyloid in the brain tissues of Alzheimer's disease model mice by inhibiting inflammatory response and oxidative stress.

The protective effect of rhein lysinate (RHL) on Alzheimer's disease (AD) was explored in senescence-accelerated mouse prone-8 (SAMP8) mice. SAMP8 mice without treatment were used as the AD-positive control, and senescence-accelerated-resistant mice were used as the AD-negative control. In this study, 4-month-old male SAMP8 mice were orally administered 25 and 50 mg/kg RHL in drinking water for 6 months.

Quality of life and emotional change for middle-aged and elderly patients with diabetic retinopathy.

Aim: To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions.

Methods: The present study included 108 diabetic retinopathy (DR) patients: 54 with PDR and 54 with non-proliferative diabetic retinopathy (NPDR). Each healthy control group (n=54) sociodemographically matched to DR groups was established respectively.

Fasting plasma insulin is associated with metabolic syndrome in farmers but not in nomads among the Mongolian population, China.

Aim: The World Health Organization (WHO) includes insulin resistance among its criteria for diagnosing metabolic syndrome (MetS); however, previous epidemiologic studies have limited their research to settled populations only. This study aims to clarify the relationship between plasma insulin and metabolic factors on a broader scale by studying data obtained from nomadic and settled Mongolian populations.

Methods: A cross-sectional epidemiologic study of 200 nomads and 256 farmers was performed in Inner Mongolia, Republic of China.

[Qualitative analysis on the denervating action of botulinum toxin A in gel].

Aim: To ascertain the bioactivity and to analyse quantificationally the denervating action of botulinum toxin A (BTXA) in gel.

Methods: 36 Sprague-Dawley rats were randomized into four groups. In group A - D, the gastrocnemius muscle of one leg was randomly selected to receive injection of BTXA solution 5U in 0.

[The clinical features and surgical treatment of masked bilateral superior oblique palsy].

Objective: To investigate the clinical features, diagnosis and the management of masked bilateral superior oblique palsy (MBSOP).

Methods: Retrospectively analyzed the records of all 7 patients that met the clinical criteria for MBSOP in Zhongshan Ophthalmic Center between 1999 and 2003. The head tilt, vertical deviation in primary position and the action of obliquus pre- and postoperatively were collected in detail.

[The effect of weakening the overaction superior oblique muscles on the status of ocular torsion].

Objective: To investigate the effect of weakening the superior oblique muscles on the status of ocular torsion.

Methods: Twenty-nine patients (58 eyes) underwent tenotomy or partial ectomy of bilateral superior oblique muscles for treatment of superior oblique overacting. Objective cyclodeviations were assessed by fundus photograph before and 7 days after the surgery.

[The effect of interleukin-1alpha on intraocular pressure in rabbit eyes and its focal side effects].

Objective: To investigate the efficiency of interleukin-1alpha on intraocular pressure reduction and its safety.

Methods: 35 New Zealand female rabbits were randomized into seven groups. In group-A, one eye was randomly selected to receive sub-conjunctival injection of 15 ng IL-1alpha, and in group B-D, one eye was injected intracamerally with IL-1alpha 1.

[Clinical features of V patterns strabismus and its long-term effect of surgical treatment].

Objective: To investigate the features and treatment of V patterns strabismus.

Methods: Pre- and post-operative deviation and oblique muscle action as well as binocular visual function were evaluated in sixty-three V pattern patients. The difference between upgaze and downgaze of deviation were recorded before and after operation.

Regioselective formation of beta-alkyl-alpha-phenyliridabenzenes via unsymmetrical 3-vinylcyclopropenes: probing steric and electronic influences by varying the alkyl ring substituent.

The synthesis of unsymmetrical (Z)-1-alkyl-3-(2-iodovinyl)-2-phenyl-1-cyclopropenes (R=Me (8 a), Et (8 b), iPr (8 c), and tBu (8 d)) and their reactions with Vaska's complex [Ir(CO)Cl(PPh3)2] and its trimethylphosphine analogue [Ir(CO)Cl(PMe3)2] were investigated. Iridabenzvalene (13/20), iridabenzene (14/21), and/or eta(5)-cyclopentadienyliridium complexes (15/22) were obtained in modest yields and were fully characterized by spectroscopic means. X-ray structural data was secured for iridabenzvalene 13 d and iridabenzenes 14 a,b,d.

Highly enantioselective asymmetric hydrogenation of beta-acetamido dehydroamino acid derivatives using a three-hindered quadrant rhodium catalyst.

[reaction: see text] A previously reported three-hindered quadrant chiral ligand and its corresponding rhodium complex provide high enantioselectivity for the asymmetric hydrogenation of beta-acetamido dehydroamino acid substrates. Both (E)- and (Z)-substrates are hydrogenated with high enantioselectivity in all of the reported examples. Asymmetric hydrogenation of a cyclic beta-acetamido dehydroamino acid substrate in 85% ee is also reported.

[The effect of weakening inferior oblique muscles on the status of ocular torsion].

Objective: To understand the clinical significance of subjective and objective examination of cyclodeviations and investigate the effect of weakening inferior oblique muscles on the status of ocular torsion.

Methods: Twenty patients (40 eyes) with overacting inferior oblique muscles underwent bilateral myotomy or partial myectomy of inferior oblique muscles. Subjective cyclodeviations were measured before surgery as well as one week, two months after surgery by double maddox rod test (DMRT).

Highly selective asymmetric hydrogenation using a three hindered quadrant bisphosphine rhodium catalyst.

A concise synthesis of both enantiomers of ligand 2 and rhodium complex 5 is presented. The crux of the synthesis is a chiral HPLC separation of the enantiomers of 4. Rhodium complex 5 possesses three hindered quadrants in the steric environment within which a substrate binds.

Stereocontrolled synthesis of angularly fused tricyclic ring systems by means of 1-metalla-1,3,5-hexatrienes (M=Cr, W).

An efficient pathway for the stereocontrolled synthesis of functionalized, angularly fused tricyclic ring systems from readily available (1-alkynyl)carbene complexes [(OC)(5)M=C(OEt)C(triple bond)CR] (M=Cr, W; R=Ph, c-C(6)H(9)) is described. The synthesis involves the formation of a 1-metalla-1,3,5-hexatriene from the (1-alkynyl)carbene tungsten complex [(OC)(5)W=C(OEt)C(triple bond)C-c-C(6)H(9)] and a secondary amine, and its thermally induced pi-cyclization to a tetrahydroindene, which undergoes a spontaneous isomerization to another tetrahydroindene. Condensation of these tetrahydroindenes with pyran-2-ylidene complexes derived from (1-alkynyl)carbene complexes [(OC)(5)M=C(OEt)C(triple bond)CPh] (M=Cr, W) proceeds smoothly giving angularly fused tricyclic ring systems, rearrangement of which may generate spiro(cyclopentane-1,1-indanes) as side products.