Publications by authors named "He-Ting Dong"
Background: Programmed death-ligand 1 (PD-L1) is an important immune checkpoint inhibitor. Recent studies suggest that the PD-L1-mediated pathway may be a promising target in allergic asthma. However, the mechanism by which PD-L1 represses neutrophilic asthma (NA) remains unclear.
View Article and Find Full Text PDFBackground: This study set out to evaluate the clinical significance and diagnostic effectiveness of serological tests and real-time polymerase chain reactions (RT-PCR) in children of different age groups and disease durations infected with Mycoplasma pneumoniae (MP).
Methods: Pediatric patients with lower respiratory tract infection (LRTI) confirmed by polymerase chain reaction (PCR) were enrolled and subjected to bronchoalveolar lavage fluid PCR (BALF-PCR) for MP infection. The diagnostic values of the serum immunoglobulin M (IgM) test, paired sera immunoglobulin G (IgG) test, RT PCR applied to nasopharyngeal aspirates (NPA-PCR), and combined IgM and NPA-PCR test were evaluated.
Article Synopsis
- - The study aimed to analyze the prevalence of respiratory adenovirus (ADV) infections among hospitalized children in Suzhou, China, over a 10-year period from 2006 to 2015.
- - Out of 35,529 children with respiratory infections, 440 were found to be ADV-positive, with infection rates increasing with age and no significant difference between boys and girls.
- - The findings indicate that ADV infections are more frequent in younger children aged 3-14, particularly during the spring and summer months compared to autumn and winter.