Publications by authors named "He-Qing Cai"

Guangxi is a typical geological high background area in southwest China, where carbonates, black rock series, basic-ultrabasic rock mass, and metal deposits (mineralized bodies) exhibit strong weathering into loam, resulting in higher cadmium (Cd) content in the soil than that in other areas of China. In order to investigate the degree of influence of mining activities on topsoil environmental quality in the area with high geological background, we chose a mining area and control area in Hezhou for this research and systematically carried out a comparative study on Cd transport routes and transport flux density in topsoil. The results showed that the average atmospheric dry and wet deposition flux densities of Cd in the soil of the mining area and control area were 1.

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Article Synopsis
  • The study investigates the safety concerns linked to graphene oxide silver nanoparticles (GO-AgNPs), highlighting their ability to increase reactive oxygen species (ROS) generation, damage DNA, and alter various RNA expressions, particularly focusing on circRNAs.
  • The experimental approach involved treating rabbit fetal fibroblast cells with different concentrations of GO-AgNPs, measuring various cellular stress indicators, and employing high-throughput sequencing to analyze RNA expression changes.
  • Results showed significant upregulation of 57 circRNAs, 75 lncRNAs, and 444 mRNAs, as well as downregulation of 35 circRNAs, 21 lncRNAs, and 186 mRNAs, indicating that these RNAs are involved in cancer-related transcriptional mis
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The widespread use of graphene oxide-silver nanoparticle nanocomposites (GO-AgNPs) in biomedical sciences is increasing the chances of human and animal exposure to its chronic non-toxic doses. Exposure to AgNPs-related nanomaterials may result in the negative effect on the dam, fetus and offspring. However, there are only little available information for profound understanding of the epigenetic alteration in the cells and animals caused by low-dose chronic exposure of GO-AgNPs.

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Graphene oxide-silver nanoparticle (GO-AgNPs) nanocomposites have drawn much attention for their potential in biomedical uses. However, the potential toxicity of GO-AgNPs in animals and humans remains unknown, particularly in the developing fetus. Here, we reported the GO-AgNP-mediated cytotoxicity and epigenetic alteration status in caprine fetal fibroblast cells (CFFCs).

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