Publications by authors named "He-Peng Yu"

Article Synopsis
  • - The wild yeast Saccharomyces paradoxus is emerging as a key model organism in ecology and evolutionary biology, but its distribution and genetic diversity in China remain largely uncharted.
  • - An extensive survey in China identified two distinct lineages of S. paradoxus: most strains belong to the Far East lineage, while six strains represent a newly discovered, highly diverged lineage.
  • - The study indicates that the Eurasian population of S. paradoxus shows higher genetic diversity compared to the American population, with more lineage-specific introgression events occurring in Eurasia.
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Article Synopsis
  • Researchers sequenced the genomes of 97 strains of the yeast Saccharomycopsis fibuligera, which is important for Chinese liquor production, to explore its genetic diversity.
  • They identified four main genetic lineages, with one containing 60 homozygous strains that are smaller in size and less diverse, while the other three lineages are heterozygous and more diverse with larger genomes.
  • Although there were significant gene variations between lineages, no major differences in enzyme activity or growth patterns were found, except for higher glucoamylase activity in the homozygous strains.
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Heterosis or hybrid vigor is a common phenomenon in plants and animals; however, the molecular mechanisms underlying heterosis remain elusive, despite extensive studies on the phenomenon for more than a century. Here we constructed a large collection of F1 hybrids of by spore-to-spore mating between homozygous wild strains of the species with different genetic distances and compared growth performance of the F1 hybrids with their parents. We found that heterosis was prevalent in the F1 hybrids at 40°C.

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Objective: Both decreased glomerular filtration rate (GFR) and arterial stiffness were considered as risk factors for atherosclerosis. Previous studies have suggested the association between central arterial stiffness and the degree of GFR loss. Whether decreased GFR contributes to peripheral artery stiffness remains controversial.

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