Laryngeal Squamous Cell Carcinoma: Clinical Significance and Potential Mechanism of Cell Division Cycle 45.

Cell division cycle 45 () plays an important role in the occurrence and development of numerous carcinomas, but its effect in laryngeal squamous cell carcinoma (LSCC) remains unclear. The messenger RNA and protein expression levels of CDC45 in LSCC were evaluated with a test and the standard mean difference (SMD). The ability of CDC45 expression to distinguish the LSCC was assessed through receiver operating characteristic (ROC) curves.

Upregulation of BIRC5 plays essential role in esophageal squamous cell carcinoma.

Background: Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers in the world, the detection and prognosis of which are still unsatisfactory. Thus, it is essential to explore the factors that may identify ESCC and evaluate the prognosis of ESCC patients.

Results: Both protein and mRNA expression levels of BIRC5 are upregulated in ESCC group rather than non-ESCC group (standardized mean difference > 0).

Resolving the quantum dynamics of near cut-off high-order harmonic generation in atoms by Bohmian trajectories.

We present an ab initio study of the quantum dynamics of high-order harmonic generation (HHG) near the cutoff in intense laser fields. To uncover the subtle dynamical origin of the HHG near the cutoff, we extend the Bohmian mechanics (BM) approach for the treatment of attosecond electronic dynamics of H and Ar atoms in strong laser fields. The time-dependent Schrödinger equation and the self-interaction-free time-dependent density functional theory are numerically solved accurately and efficiently by means of the time-dependent generalized pseudospectral method for nonuniform spatial discretization of the Hamiltonian.