A tooth-bearing mandible fossil of a colobine monkey discovered at Shuitangba, Zhaotong, Yunnan, China, was morphometrically analyzed and compared with extant Asian colobines. Our previous qualitative and quantitative descriptions indicate that it can be safely attributed to Mesopithecus pentelicus, a Miocene fossil colobine widely found in Europe and South Asia. The present research aims to explore fossil association with extant colobines and functionally propose its dietary preferences based on multivariate morphometric analyses of mandibular morphology.
View Article and Find Full Text PDFObjective: Due to the limited operating space in the magnetic resonance (MR) environment, there is coupled motion in the insertion mechanism, which not only reduces the flexibility of the robot but also challenges the insertion path planning. Meanwhile, the path planning is also restricted by the bending rule of the flexible needle, thus the bending model of the needle is also essentially built.
Approach: This paper proposes a path planner for the flexible needle based on both the coupled motion kinematics of the insertion robot and the bending model of the flexible needle.
Most of the existing SERS systems failed to achieve satisfactory results in early diagnosis of Alzheimer's disease owing to a lack of effective signal transduction. Herein, we developed a dual signal amplification strategy for SERS detection of amyloid-β oligomers based on proximity hybridization-triggered catalyzed hairpin assembly (CHA) and hybridization chain reaction (HCR). In the presence of the target protein and two DNA-labeled antibodies, a proximate complex formed in a homogeneous solution.
View Article and Find Full Text PDFThe accurate identification of traffic loads acting on bridges provides an effective basis for the traffic control and operation of in-service bridges. To improve the efficiency and accuracy of loading identification, we propose an efficient multiparameter identification method with a Legendre neural network (LNN) for the monitoring of traffic loads across the full spatiotemporal domain. Compared to conventional studies that suffer from ill-posed problems and neural network-based means that lack a physically interpretable model, with the proposed strategy, both the explicit expression and time histories of the traffic load can be simultaneously obtained.
View Article and Find Full Text PDFCorrection for 'Melatonin as an inducer of arecoline and their coordinated roles in anti-oxidative activity and immune responses' by Xiaojian Yin , , 2020, , 8788-8799, https://doi.org/10.1039/D0FO01841D.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
TiMn based multinary alloys make full use of the high abundance of rare earth resources in attractive applications of hydrogen storage but suffer from mediocre hydrogen ab/desorption kinetics and lack the in-depth mechanism analysis of hydrogenation/dehydrogenation behavior. Herein, on the basis of current research on compositional modulation, we utilize the low-cost powder metallurgy method to prepare TiZrMnCrV (x = -0.05, 0, 0.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2024
Introduction: , , , and are the primary pathogens responsible for gastrointestinal diseases in pigs, posing a significant threat to the health and productivity of pig production systems. Pathogen detection is a crucial tool for monitoring and managing these infections.
Methods: We designed primers and probes targeting the gene of , the 23S gene of , the gene of , and the gene of .
Front Nutr
November 2024
[This corrects the article DOI: 10.3389/fnut.2024.
View Article and Find Full Text PDFIntroduction: (SS) is one of the most important pathogens causing major economic losses in the global pig farming industry and is a serious threat to public health safety. It has multiple serotypes, with poor cross-protection between serotypes, and effective typing methods are lacking.
Methods: In this study, a quadruplex TaqMan fluorescence quantitative PCR assay that can differentiate between types 2, 7 and 9 was developed using the gene, a generic gene for , and , and , genes encoding podocarp-associated genes for types 2, 7 and 9, respectively, as targets.
Int Arch Allergy Immunol
December 2024
Purpose: Kidney transplantation is the optimal therapy for end-stage renal disease, but pre-transplant malignancy (PTM) is a concern due to the increased risk of cancer recurrence with immunosuppression. While advancements in immunosuppression and cancer treatments have improved kidney recipient and graft survival, the impact of PTM on survival remains unclear and warrants comprehensive assessment.
Methods: This systematic review and meta-analysis followed PRISMA guidelines.
To address the conservative excavator working device configuration obtained by traditional design methods, a lightweight structure design method was proposed in this study based on automatically generated surrogate model. A finite element model of the working device was first constructed, and its accuracy was verified against experimental results. By incorporating the Gini coefficient to compute the information entropy pertaining to the relationship between variables and responses, the entropy-weighted TOPSIS method has been significantly enhanced.
View Article and Find Full Text PDFBackground: Saturated biopsy is widely used in a histopathological examination of prostate biopsy surgery by expanding the target regions and the increasing the number of insertions.
Methods: The paper proposed a path planning algorithm for multiple targets with a single entry for a cannula flexible needle with variable curvatures. The algorithm is based on modified rapidly-exploring random trees (RRTs), and the variable-curvature motions of the flexible needle are used to achieve optimal path.
Aimed at addressing the problem of azimuth measurement of a short-range target with a pulsed laser, a new, to our knowledge, azimuth measurement method based on a single-pulse laser beam expanding mechanism is proposed based on the research of the pulse laser dynamic/static azimuth detection method. The echo power equation of single-pulse laser beam expanding short-range detection is derived theoretically. Combined with the spatial geometric distribution of the optical path and the normalized sum-difference angle measurement algorithm of the four-quadrant detector, a single-pulse laser short-range azimuth angle calculation model is established.
View Article and Find Full Text PDFThe interfacial photothermal-photocatalytic systems can generate clean water while purifying wastewater containing organic pollutants, but the impact of thermal convection on synergistic effects remains unexplored. This paper aims to regulate the thermal convection at the interface to significantly enhance the synergistic effect of interfacial photothermal-photocatalytic systems. A novel heterogeneous structure comprising iron-based metal-organic frameworks and multi-walled carbon nanotubes with a gelatin-polyvinyl alcohol (PVA) double network hydrogel (MWCNTs@NM88B/PVA/gelatin hydrogel, denoted as MMH) is developed and employed in the construction of the solar-driven interfacial evaporation (SIE) system.
View Article and Find Full Text PDFSheng Wu Gong Cheng Xue Bao
November 2024
Vaccination is the most effective measure for reducing and preventing influenza and related complications. In this study, we analyzed the mutation trend and the antigen dominant site changes of the amino acid sequence of hemagglutinin subunit 1 (HA1) of human influenza A virus (IAV) in the northern hemisphere from 2012 to 2022. According to the HA1 sequences of A/Darwin/6/2021 (H3N2) and A/Wisconsin/588/2019 (H1N1) recommended by the World Health Organization in the 2022 influenza season in northern hemisphere, we employed the mosaic algorithm to design three Mosaic-HA1 antigens through stepwise substitution.
View Article and Find Full Text PDFThe deposition of anthocyanin plays a crucial role in fruit pigmentation and serves as the primary determinant of pear quality. Various factors influence the synthesis of anthocyanins, with salicylic acid playing a significant role among them. However, the mechanism by which salicylic acid affects anthocyanin synthesis remains unclear.
View Article and Find Full Text PDFRiver ecosystems face escalating challenges due to altered flow regimes from human activities, such as urbanization with hydrological modifications. Understanding the role of microbial communities for ecosystems with changing flow regimes is still incomplete and remains at the frontier of aquatic microbial ecology. In particular, influences of riverine backward flow on the aquatic biota remain largely unknown.
View Article and Find Full Text PDFThe CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation. We applied selective ribosome profiling to further investigate the determinants of CCR4-NOT recruitment to ribosomes in mammalian cells.
View Article and Find Full Text PDFPurpose: Currently, detethering surgery (DS) is the modality most extensively utilized to treat primary Tethered cord syndrome (TCS). Disappointingly, some children without bladder impairment showed a deterioration of bladder function after surgery, which critically influences the health-related quality of life. It was hypothesized that the DS might have a significant effect on bladder function and psychology.
View Article and Find Full Text PDF