Development of a Synthetic VP1 Protein Peptide-Based ELISA to Detect Antibodies Against Porcine Bocavirus Group 3.

Porcine bocavirus (PBoV), classified within the genus Bocaparvovirus, has been reported worldwide. PBoV has been divided into group 1, group 2, and group 3. PBoV group 3 (G3) viruses are the most prevalent in China.

Correction: Chen et al. The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment. 2023, 1568.

In the original publication [...

Diamine Crosslinked Addition-Type Diblock Poly(Norbornene)s-Based Anion Exchange Membranes with High Conductivity and Stability for Fuel Cell Applications.

Anion exchange membranes (AEMs) as a kind of important functional material are widely used in fuel cells. However, synthetic AEMs generally suffer from low conductivity, poor alkaline stability, and poor dimensional stability. Constructing efficient ion transport channels is widely regarded as one of the most effective strategies for developing AEMs with high conductivity and low swelling ratio.

The Role of ClpV in the Physiology and Pathogenicity of subsp. Strain zlm1908.

subsp. () is a Gram-negative bacterium responsible for citrus canker, a significant threat to citrus crops. ClpV is a critical protein in the type VI secretion system (T6SS) as an ATPase involved in bacterial motility, adhesion, and pathogenesis to the host for some pathogenic bacteria.

Effects of Biological Nitrogen Fixation and Nitrogen Deposition on Soil Microbial Communities in Karst Grassland Ecosystems.

Diverse exogenous nitrogen (N) sources have a considerable impact on microbial community structure in terrestrial ecosystems. Legume plants and N deposition can relieve N limitations and increase net primary productivity. However, the differences in their effects on soil microbial communities remain unclear.

Laterally Excited Resonators Based on Single-Crystalline LiTaO Thin Film for High-Frequency Applications.

High-performance acoustic resonators based on single-crystalline piezoelectric thin films have great potential in wireless communication applications. This paper presents the modeling, fabrication, and characterization of laterally excited bulk resonators (XBARs) utilizing the suspended ultra-thin (~420 nm) LiTaO (LT, with 42° YX-cut) film. The finite element analysis (FEA) was performed to model the LT-based XBARs precisely and to gain further insight into the physical behaviors of the acoustic waves and the loss mechanisms.

Construction of Heterostructured NiS@V-NiFe(III) LDH for Enhanced OER Performance.

The oxygen evolution reaction (OER), which involves a four-electron transfer and slow kinetics, requires an efficient catalyst to overcome the high energy barrier for high-performance water electrolysis. In this paper, a novel NiS@V-NiFe(III) LDH/NF catalyst was prepared via a facile two-step hydrothermal method. The constructed heterostructure of NiS@V-NiFe(III) LDH increases the specific surface area and regulates the electronic structure.

Adsorption and Removal of 2,4,6-Trinitrotoluene by a Glycoluril-Derived Molecular-Clip-Based Supramolecular Organic Framework.

A glycoluril-derived molecular-clip-based supramolecular organic framework (clip-SOF) with intrinsic porosity was prepared. The clip-SOF was used for the adsorption and removal of 2,4,6-trinitrotoluene (TNT) driven by noncovalent interactions. The efficiency of TNT removal by clip-SOFs is up to 88.

Preparation of Green Tea Polyphenol-Loaded Diacylglycerol Nanostructured Lipid Carrier Hydrogels and Their Activities Related to Skin Protection.

Diacylglycerol (DAG) is a functional oil but is rarely used in the cosmetic industry because low solubility, susceptibility to leakage and low viscosity to skin are still the main hurdles. A novel diacylglycerol nanostructured lipid carrier hydrogel (GTP-DAG-NLC-GEL) loaded with green tea polyphenol (GTP) was designed and successfully prepared to broaden DAG's application in cosmetics, which significantly improved GTP stability and skin stickiness of DAG. The results showed that DAG-NLC-GEL had good viscosity, which was 980 Pa·s when the shear rate was 5 rpm, and its viscosity decreased quickly with the increase in shear rate, making it easily expand on skin.

Establishment and Application of an Elastic-Plastic Damage Constitutive Model for Ceramic Fiber Insulation Tiles.

A thermal protection system is critical for ensuring the safe take-off and return of various aircraft. A key heat-resistant material within this system is the ceramic fiber insulation tile (CFIT), which is a porous three-dimensional network material with density ranges from 0.3 to 0.

Genetic Diversity and Differentiation of Silkworm () Local Germplasm Resources in China and Uzbekistan.

Silkworm () is an economically significant insect that produces silk and makes important contributions to the development of silk-producing countries. The genetic diversity and unique adaptive traits of silkworm germplasm resources form the foundation for breeding efforts. In various geographical regions, silkworm have developed distinct traits through long-term adaptive selection.

Current Advances and Future Directions of Pluripotent Stem Cells-Derived Engineered Heart Tissue for Treatment of Cardiovascular Diseases.

Cardiovascular diseases resulting from myocardial infarction (MI) remain a leading cause of death worldwide, imposing a substantial burden on global health systems. Current MI treatments, primarily pharmacological and surgical, do not regenerate lost myocardium, leaving patients at high risk for heart failure. Engineered heart tissue (EHT) offers a promising solution for MI and related cardiac conditions by replenishing myocardial loss.

Federated Collaborative Learning with Sparse Gradients for Heterogeneous Data on Resource-Constrained Devices.

Federated learning enables devices to train models collaboratively while protecting data privacy. However, the computing power, memory, and communication capabilities of IoT devices are limited, making it difficult to train large-scale models on these devices. To train large models on resource-constrained devices, federated split learning allows for parallel training of multiple devices by dividing the model into different devices.

The relationship between sleep duration and frailty: findings from the China Health and Retirement Longitudinal Study.

Background: Research investigating the association between sleep duration and the risk of frailty has yielded conflicting results. This study used data from the China Health and Retirement Longitudinal Study (CHARLS) to investigate the association between sleep duration and frailty.

Methods: Participants aged 45 and above at baseline were included in this study.

CD24-Fc resolves inflammation and rescues CD8 T cells with polyfunctionality in humanized mice infected with HIV-1 under cART.

Unlabelled: The persistence of HIV-1 reservoirs during combination anti-retroviral therapy (cART) leads to chronic immune activation and systemic inflammation in people with HIV (PWH), associating with a suboptimal immune reconstitution as well as an increased risk of non-AIDS events. This highlights the needs to develop novel therapy for HIV-1 related diseases in PWH. In this study, we assessed the therapeutic effect of CD24-Fc, a fusion protein with anti-inflammatory properties that interacts with danger-associated molecular patterns (DAMPs) and siglec-10, in chronic HIV-1 infection model using humanized mice undergoing suppressive cART.

Identification of the locus controlling leaf rolling and its application in maize breeding.

Unlabelled: Increasing planting density is one of the most important strategies for generating higher maize yields. Moderate leaf rolling decreases mutual shading of leaves and increases the photosynthesis of the population and hence increases the tolerance for high-density planting. Few genes that control leaf rolling in maize have been identified, however, and their applicability for breeding programs remains unclear.

Electrolyte-Gated Ionic Transistor for Highly Sensitive and Selective Iontronic Sensing.

Iontronic sensors based on confined space have garnered significant attention due to their promising applications, ranging from single-cell analysis to studies. However, their limited sensitivity has constrained their effectiveness in studying molecular information during physiological and pathological processes. Here, we demonstrate an electrolyte-gated ionic transistor (EGIT) by integrating the confined ion transport behavior in a double-barreled micropipet with an electrolyte-gated transistor configuration, achieving highly sensitive and selective sensing.

Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus.

Brain-resident macrophages, microglia, have been proposed to have an active role in synaptic refinement and maturation, influencing plasticity and circuit-level connectivity. Here we show that several neurodevelopmental processes previously attributed to microglia can proceed without them. Using a genetically modified mouse that lacks microglia (Csf1r), we find that intrinsic properties, synapse number and synaptic maturation are largely normal in the hippocampal CA1 region and somatosensory cortex at stages where microglia have been implicated.

Parasitic structure defect blights sustainability of cobalt-free single crystalline cathodes.

Recent efforts to reduce battery costs and enhance sustainability have focused on eliminating Cobalt (Co) from cathode materials. While Co-free designs have shown notable success in polycrystalline cathodes, their impact on single crystalline (SC) cathodes remains less understood due to the significantly extended lithium diffusion pathways and the higher-temperature synthesis involved. Here, we reveal that removing Co from SC cathodes is structurally and electrochemically unfavorable, exhibiting unusual voltage fade behavior.

Dynamin-Related Protein 1 Orchestrates Inflammatory Responses in Periodontal Macrophages via Interaction With Hexokinase 1.

Aim: To explore the potential roles of mitochondrial dysfunction in the initiation of inflammation in periodontal macrophages and to determine the mechanism underlying the involvement of dynamin-related protein 1 (Drp1) in macrophage inflammatory responses through its interaction with hexokinase 1 (HK1).

Materials And Methods: Gingival tissues were collected from patients diagnosed with periodontitis or from healthy volunteers. Drp1 tetramer formation and phosphorylation were analysed using western blot.

Gut microbiota: A new key of understanding for Panax notoginseng against multiple disorders and biotransformation.

Ethnopharmacological Relevance: Panax notoginseng (Burkill) F.H.Chen(P.

Sugarcane Pan-Transcriptome Identifying a Master Gene Regulating Lignin and Sugar Traits.

Sugarcane has the most complex polyploid genome in the world, and sugar-related traits are one of the most important aims in sugarcane breeding. It is essential to construct a representative pan-transcriptome that contains all transcripts of a species for studies on genetic diversity, population expression, and omics analyses in sugarcane. In this study, we constructed the first comprehensive pan-transcriptome for sugarcane, and 8434 highly reliable open reading frames were found, which were not aligned with any published sugarcane genome.

Single-Cell RNA Sequencing Uncovers Molecular Features Underlying the Disrupted Neurogenesis Following Traumatic Brain Injury.

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, with limited effective treatment strategies. Endogenous neural stem cells (NSCs) give rise to neurons and glial cells throughout life. However, NSCs are more likely to differentiate into glial cells rather than neurons at the lesion site after TBI and the underlying molecular mechanism remains largely unknown.

Nonviral targeted mRNA delivery: principles, progresses, and challenges.

Messenger RNA (mRNA) therapeutics have garnered considerable attention due to their remarkable efficacy in the treatment of various diseases. The COVID-19 mRNA vaccine and RSV mRNA vaccine have been approved on the market. Due to the inherent nuclease-instability and negative charge of mRNA, delivery systems are developed to protect the mRNA from degradation and facilitate its crossing cell membrane to express functional proteins or peptides in the cytoplasm.