A Lightweight Deep Learning Network with an Optimized Attention Module for Aluminum Surface Defect Detection.

Aluminum is extensively utilized in the aerospace, aviation, automotive, and other industries. The presence of surface defects on aluminum has a significant impact on product quality. However, traditional detection methods fail to meet the efficiency and accuracy requirements of industrial practices.

External nitrogen influxes hinder the efficacy of lanthanum-modified bentonite (LMB) on phosphorus and algae control in shallow lakes.

Regulating internal and external phosphorus (P) holds a predominant position in eutrophication management of lakes and other water bodies, with less emphasis on controlling nitrogen (N) due to the presence of N-fixing cyanobacteria. Nonetheless, external N influxes may stimulate the proliferation of non-N-fixing cyanobacteria, thereby fostering cyanobacteria blooms during summer seasons. To elucidate the significance of N regulation, a two-factor orthogonal experiment was performed to study the influences of external N input on the efficacy of lanthanum-modified bentonite (LMB), a sediment capping material for P immobilization.

Conjugation of Multiple Proteins Onto the Surface of PLGA/Lipid Hybrid Nanoparticles.

Nanoparticles are increasingly being used in the development of vaccines for disease prevention or treatment. Recent research has demonstrated that conjugating a protein onto the surface of nanoparticles can significantly increase its immunogenicity. Considering various pathogens that threaten human health, multivalent vaccines are often desirable.

Bright compact ultrabroadband source by orthogonal laser-sustained plasma.

Laser-sustained plasma (LSP) source featuring high brightness and broadband spectral coverage is found to be powerful in various fields of scientific and industrial applications. However, the fundamental limit of low conversion efficiency constrains the system compactness and widespread applications of such broadband light sources. In this paper, we propose an innovative orthogonal LSP to break through the conversion efficiency limitation.

LINC00460/miR-186-3p/MYC feedback loop facilitates colorectal cancer immune escape by enhancing CD47 and PD-L1 expressions.

Background: Long non-coding RNAs (LncRNAs) have been implicated as critical regulators of cancer tumorigenesis and progression. However, their functions and molecular mechanisms in colorectal cancer (CRC) still remain to be further elucidated.

Methods: LINC00460 was identified by differential analysis between human CRC and normal tissues and verified by in situ hybridization (ISH) and qRT-PCR.

Integrating High-Performance Flexible Wires with Strain Sensors for Wearable Human Motion Detection.

Flexible electronics have revolutionized the field by overcoming the rigid limitations of traditional devices, offering superior flexibility and adaptability. Conductive ink performance is crucial, directly impacting the stability of flexible electronics. While metal filler-based inks exhibit excellent conductivity, they often lack mechanical stability.

Facile Preparation of Tough, Puncture-Resistant Antibacterial Polyrotaxane Hydrogel.

Slide-ring hydrogels containing polyrotaxane structures have been widely developed, but current methods are more complex, in which modified cyclodextrins, capped polyrotaxanes, and multistep reactions are often needed. Here, a simple one-pot method dissolving the pseudopolyrotaxane (pPRX) in a mixture of acrylamide and boric acid to form a slide-ring hydrogel by UV light is used to construct a tough, puncture-resistant antibacterial polyrotaxane hydrogel. As a new dynamic ring cross-linking agent, boric acid effectively improves the mechanical properties of the hydrogel and involves the hydrogel with fracture toughness.

PGE2 binding to EP2 promotes ureteral stone expulsion by relaxing ureter via the cAMP-PKA pathway.

Background: This study investigated the relaxation effect of PGE2 on the ureter and its role in promoting calculi expulsion following calculi development.

Methods: By using immunofluorescence and Western blot, we were able to locate EP receptors in the ureter. In vitro experiments assessed the impact of PGE2, receptor antagonists, and agonists on ureteral relaxation rate.

Csn-miR156d-CsSPL1 regulates flowering and anthocyanin metabolism.

MiR156 play important roles in regulation of plant growth and development, secondary metabolite synthesis, and other biological processes by targeting the SQUAMOSA promoter binding protein-like (SPL) family. Our previous sequencing data analysis suggested that Csn-miR156d may regulate flowering and anthocyanin accumulation by cleavage and degradation of the expression of the SPL in tea plant, but it remains to be elucidated. In this study, 5'RLM-RACE experiment, tobacco transient transformation, qRT-PCR, and antisense oligonucleotide (asODN) were used to verify that CsSPL1 is the target gene of Csn-miR156d.

Efficacy and Safety of Endoscopic Surgery Versus Craniotomy for Hypertensive Putamen Hemorrhage.

Objective: This study aimed to evaluate the efficacy and safety of neuroendoscopy for treating hypertensive putamen hemorrhage (HPH), compared with traditional craniotomy.

Methods: We retrospectively analyzed 81 consecutive patients with HPH treated with neuroendoscopy (n=36) or craniotomy (n=45) in the Department of Neurosurgery at the Anhui Provincial Hospital Affiliated to Anhui Medical University between January 2015 and December 2017. We compared the clinical and radiographic outcomes, excluded 14 patients who did not meet the inclusion criteria.

SIRT1 regulates endoplasmic reticulum stress-related organ damage.

Endoplasmic reticulum (ER) stress plays a key role in the pathogenesis of several organ damages. Studies show that excessive ER stress (ERS) can destroy cellular homeostasis, causing cell damage and physiological dysfunction in various organs. In recent years, Sirtuin1 (SIRT1) has become a research hotspot on ERS.

maresin2 fine-tunes ULK1 O-GlcNAcylation to improve post myocardial infarction remodeling.

Background: Myocardial infarction (MI) is one of the common causes of hospitalization and death all over the world. Maresin2 (MaR2), a specialized pro-solving mediator of inflammation, has been consolidated to be a novel cytokine fine-tuning inflammatory cascade. However, the precise mechanism is still unknown.

Climate-associated variation in the drivers of benthic macroinvertebrate species-area relationships across shallow freshwater lakes.

The island species-area relationship (ISAR) describes how species richness increases with increasing area of a given island or island-like habitat, such as freshwater lakes. While the ISAR is one of the most common phenomena observed in ecology, there is variation in both the form of the relationship and its underlying mechanisms. We compiled a global data set of benthic macroinvertebrates from 524 shallow freshwater lakes, ranging from 1 to 293,300 ha in area.

Promotion of improved intestinal barrier health by soybean-derived bioactive peptides in Chinese mitten crab () fed a low fishmeal diet.

To alleviate the growth inhibition, and intestinal damage of Chinese mitten crab () induced by low fishmeal diets (LF), an 8-week feeding trial was conducted to evaluate the addition of dietary soybean-derived bioactive peptides (SBP) in LF diets on the regulation of growth, digestion and intestinal health. The crabs were fed isonitrogenous and isoenergetic conventional diet and LF diets (10 % fishmeal replaced by soybean meal, LF) supplemented with 0, 1 %, 2 %, 4 % and 6 % SBP, respectively. The results showed that LF diet inhibited growth while inclusion of SBP quadratically remitted the growth inhibition induced by LF.

Preliminary assessment of carbonic acid dissociation constants: Insights from observations in China's east coastal oceans.

Based on observations in China's east coastal oceans, we conducted a preliminary assessment of 16 sets of carbonic acid dissociation constants (K* and K*) by comparing spectrophotometrically measured pH values at 25 °C with those calculated from total alkalinity and dissolved inorganic carbon. We obtained that K* and K* often performed differently within different salinity ranges, and that the constants of Millero et al. (2002) (M02) demonstrated the best performance for the salinity range of 24-35.

Top-down effects of filter-feeding fish and bivalves moderate bottom-up effects of nutrients on phytoplankton in subtropical shallow lakes: An outdoor mesocosm study.

Biomanipulation has been widely used in the ecological restoration of eutrophic lakes for decades. However, biomanipulation is prone to failure if external nutrient loads are not reduced. In order to explore the importance of filter-feeding fish and bivalves on algal control, an outdoor mesocosm experiment was conducted using different nutrient concentrations.

An integrated transcriptomic and metabolic phenotype analysis to uncover the metabolic characteristics of a genetically engineered strain expressing gene.

Introduction: () has been extensively utilized as human food or animal feed additives. With its ability to support heterologous gene expression, proves to be a valuable platform for the synthesis of proteins and metabolites that possess both high nutritional and economic value. However, there remains a dearth of research focused on the characteristics of through genomic, transcriptomic and metabolic approaches.

Diversity and functional prediction of fungal communities in different segments of mongolian horse gastrointestinal tracts.

Background: Anaerobic fungi are effective fibre-degrading microorganisms in the digestive tract of horses. However, our understanding of their diversity and community structure is limited, especially in different parts of the gastrointestinal tract.

Results: For the first time, high-throughput sequencing technology was used to analyse and predict fungal microbial diversity in different parts of the gastrointestinal tract of Mongolian horses.

Simultaneous increases of filter-feeding fish and bivalves are key for controlling cyanobacterial blooms in a shallow eutrophic lake.

Eutrophication and cyanobacterial blooms have severely affected many freshwater ecosystems. We studied the effects of filter-feeding fish and bivalves on algal populations using a mesocosm experiment and long-term monitoring data from Lake Taihu (China). The mesocosm study, comprised of a two-way factorial design with the clam Corbicula fluminea and the fish Aristichthys nobilis at three biomass levels, resulted in lower chlorophyll a (Chl a) in high fish treatments, but no significant differences in the low and medium fish treatments.

Comparison of endoscopic evacuation, craniotomy, and puncture aspiration for the treatment of spontaneous basal ganglia intracerebral hematoma.

Objective: To compare the prognosis of patients with spontaneous basal ganglia intracerebral hematoma treated by endoscopic evacuation, craniotomy, or puncture aspiration.

Methods: This retrospective observational study included information from patients with basal ganglia hematoma who received craniotomy, endoscopic evacuation, or puncture aspiration in the Department of Neurosurgery of the First Affiliated Hospital of USTC between January 2016 and May 2021. Patients were grouped according to their treatment method for comparison.

Bi-MOF-Derived Carbon Wrapped Bi Nanoparticles Assembly on Flexible Graphene Paper Electrode for Electrochemical Sensing of Multiple Heavy Metal Ions.

The development of nanohybrid with high electrocatalytic activity is of great significance for electrochemical sensing applications. In this work, we develop a novel and facile method to prepare a high-performance flexible nanohybrid paper electrode, based on nitrogen-doped carbon (NC) wrapped Bi nanoparticles (Bi-NPs) assembly derived from Bi-MOF, which are decorated on a flexible and freestanding graphene paper (GP) electrode. The as-obtained Bi-NPs encapsulated by an NC layer are uniform, and the active sites are increased by introducing a nitrogen source while preparing Bi-MOF.

Research on the initiation pressure criterion of directional hydraulic fracturing in coal mine.

Directional hydraulic fracturing (DHF) is more and more widely used in coal mines in China for hard roof and coal burst control. The key to this technology is to determine the crack initiation pressure that affected by the shape of the artificial notch and the stress state around the fracturing hole. Reasonable and simple formula for fracturing pressure calculation is essential since the fracturing pump used in coal mines is usually limited by the harsh conditions and hardly replaced once selected.

The Effects of Intraguild Predation on Phytoplankton Assemblage Composition and Diversity: A Mesocosm Experiment.

Intraguild predation (IGP) can have a significant impact on phytoplankton biomass, but its effects on their diversity and assemblage composition are not well understood. In this study, we constructed an IGP model based on the common three-trophic food chain of "fish (or shrimp)-large branchiopods ()-phytoplankton", and investigated the effects of IGP on phytoplankton assemblage composition and diversity in outdoor mesocosms using environmental DNA high-throughput sequencing. Our results indicated that the alpha diversities (number of amplicon sequence variants and Faith's phylogenetic diversity) of phytoplankton and the relative abundance of Chlorophyceae increased with the addition of , while similar trends were found in alpha diversities but with a decrease in the relative abundance of Chlorophyceae in the treatment.