Functional genomics analysis reveals the evolutionary adaptation and demographic history of pygmy lorises.

Lorises are a group of globally threatened strepsirrhine primates that exhibit many unusual physiological and behavioral features, including a low metabolic rate, slow movement, and hibernation. Here, we assembled a chromosome-level genome sequence of the pygmy loris () and resequenced whole genomes from 50 pygmy lorises and 6 Bengal slow lorises (). We found that many gene families involved in detoxification have been specifically expanded in the pygmy loris, including the gene family, with many newly derived copies functioning specifically in the liver.