Health and wellbeing of staff working at higher education institutions globally during the post-COVID-19 pandemic period: evidence from a cross-sectional study.

Background: The ongoing global crisis of Higher Education (HE) institutions during the post-COVID-19 pandemic period has increased the likelihood of enduring psychological stressors for staff. This study aimed to identify factors associated with job insecurity, burnout, psychological distress and coping amongst staff working at HE institutions globally.

Methods: An anonymous cross-sectional study was conducted in 2023 with staff at HE institutions across 16 countries.

Burden and distribution of mortality due to sepsis and severe infection in children and adolescents in Aotearoa/New Zealand.

Aim: The aims of this research were to determine the mortality from sepsis and severe infection in the paediatric and adolescent populations of Aotearoa/New Zealand, and to determine the distribution of mortality by sub-populations.

Methods: We used three different methods to identify deaths from sepsis and severe infection and compared the groups: All deaths primarily coded with any ICD-10-AM code relating to sepsis; The presence of A40, A41 and P36 in any cause of death field; Deaths due to pneumonia and meningitis. Cases were selected from a national mortality database, with cause of death as ascribed in the national mortality collection for the years 2002-2020 inclusive.

Social media in undergraduate teaching and learning: A scoping review protocol.

Objective: To conduct a scoping review that systematically examines the body of research on social media in undergraduate teaching and learning in order to identify key issues, trends, gaps, and needs. Our objectives include determining what methods have been commonly used to study social media in undergraduate teaching and learning, and to synthesise insights from published research findings within the fields of higher education, educational technology, and the scholarship of teaching and learning.

Introduction: The use of social media technologies in post-secondary environments has been increasing over time, and especially following the shift to remote teaching and learning during the COVID-19 pandemic, this growth has continued.

Sport Participation for People with Disabilities: Exploring the Potential of Reverse Integration and Inclusion through Wheelchair Basketball.

Reverse integration is defined as the inclusion of able-bodied people into disability sport. For decades, there have been movements towards integrating people with a disability in mainstream society. There has been a lack of research supporting the movement of able-bodied involvement in disability sport, known as reverse integration.

Supporting the integration of first-year undergraduate widening participation sport students into university: the role of online programme induction.

Programme induction activities are a central feature for supporting successful student entry into university, playing an important role in ensuring they quickly settle, feel included, are motivated to learn and able to form new friendships and networks with peers and staff. Research shows how entering university can be complex and challenging for all students regardless of background and experience. This is particularly the case for widening participation students, who often encounter excessive social exclusion and financial pressures.

Online learning in higher education in the UK: Exploring the experiences of sports students and staff.

During the Covid-19 pandemic, the majority of higher education programs were delivered online and programs involving practical sessions were unable to deliver these activities on campus. This study explores the perspectives of students and staff from the sport department at a United Kingdom (UK) university. Undergraduate students (N = 21) and members of staff (N = 10) who taught on the same programs took part in online focus groups and one-to-one semi-structured interviews respectively.

Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)-but how?

We earlier reported that coating poorly water-soluble drugs with nano-hydroxyapatite (nano-HAP) improves bioavailability after oral administration. In the present study, we coated BCS Class IV drug acetazolamide (AZ) with nano-HAP (AZ/HAP formulation), and investigated its bioavailability and nano-HAP's role in promoting it. We tested AZ bioavailability after a single oral dose of the AZ/HAP formulation in rats, followed by a series of in vitro, ex vivo and in vivo testing.

A Case Study of Eukaryogenesis: The Evolution of Photoreception by Photolyase/Cryptochrome Proteins.

Eukaryogenesis, the origin of the eukaryotes, is still poorly understood. Herein, we show how a detailed all-kingdom phylogenetic analysis overlaid with a map of key biochemical features can provide valuable clues. The photolyase/cryptochrome family of proteins are well known to repair DNA in response to potentially harmful effects of sunlight and to entrain circadian rhythms.

Can nano-hydroxyapatite permeate the oral mucosa? A histological study using three-dimensional tissue models.

Nano-hydroxyapatite is used in oral care products worldwide. But there is little evidence yet whether nano-hydroxyapatite can enter systemic tissues via the oral epithelium. We investigated histologically the ability of two types of nano-hydroxyapatite, SKM-1 and Mi-HAP, to permeate oral epithelium both with and without a stratum corneum, using two types of three-dimensional reconstituted human oral epithelium, SkinEthic HGE and SkinEthic HOE respectively with and without a stratum corneum.

Entorhinal Neurons Exhibit Cue Locking in Rodent VR.

The regular firing pattern exhibited by medial entorhinal (mEC) grid cells of locomoting rodents is hypothesized to provide spatial metric information relevant for navigation. The development of virtual reality (VR) for head-fixed mice confers a number of experimental advantages and has become increasingly popular as a method for investigating spatially-selective cells. Recent experiments using 1D VR linear tracks have shown that some mEC cells have multiple fields in virtual space, analogous to grid cells on real linear tracks.

Floxed-Cassette Allelic Exchange Mutagenesis Enables Markerless Gene Deletion in Chlamydia trachomatis and Can Reverse Cassette-Induced Polar Effects.

As obligate intracellular bacteria, spp. have evolved numerous, likely intricate, mechanisms to create and maintain a privileged intracellular niche. Recent progress in elucidating and characterizing these processes has been bolstered by the development of techniques enabling basic genetic tractability.

Disrupting the Grid Cells' Need for Speed.

Hinman et al. demonstrate the presence of two speed signals in the rodent medial entorhinal cortex that are differentially affected by muscimol inactivation of medial septum. The results reveal important constraints on several computational models of grid cell firing.

Neural encoding of large-scale three-dimensional space-properties and constraints.

How the brain represents represent large-scale, navigable space has been the topic of intensive investigation for several decades, resulting in the discovery that neurons in a complex network of cortical and subcortical brain regions co-operatively encode distance, direction, place, movement etc. using a variety of different sensory inputs. However, such studies have mainly been conducted in simple laboratory settings in which animals explore small, two-dimensional (i.

Grid cells on steeply sloping terrain: evidence for planar rather than volumetric encoding.

Neural encoding of navigable space involves a network of structures centered on the hippocampus, whose neurons -place cells - encode current location. Input to the place cells includes afferents from the entorhinal cortex, which contains grid cells. These are neurons expressing spatially localized activity patches, or firing fields, that are evenly spaced across the floor in a hexagonal close-packed array called a grid.

How cumulative error in grid cell firing is literally bounded by the environment.

In this issue of Neuron, Hardcastle et al. (2015) show that the spatial firing patterns of grid cells accumulate error, drifting coherently, until reset by encounters with environmental boundaries. These results reveal important aspects of the neural dynamics of self-localization from self-motion and environmental information.

Infant suffocation in place of sleep: New Zealand national data 2002-2009.

Background: Accidental suffocation during sleep, leading to death, has been described as due to overlay or wedging of infants, particularly in a bed-sharing situation. Bed sharing is a risk factor for sudden infant death syndrome but the mechanism of death is not clearly defined. Accidental suffocation may be one such mechanism.

Subdural hemorrhage and hypoxia in infants with congenital heart disease.

Background And Objectives: It has been suggested that there is a causal relationship between hypoxia and subdural hemorrhage (SDH) in infancy. The purpose of this study was to review the incidence of SDH in infants with congenital heart disease and explore the relationship between SDH and hypoxia.

Methods: Review of data collected for a prospective longitudinal cohort study of infants undergoing surgery for congenital heart disease in New Zealand and Australia.

Outbreak of variant hand-foot-and-mouth disease caused by coxsackievirus A6 in Auckland, New Zealand.

Hand-foot-and-mouth disease is a common, usually mild childhood illness caused by enteroviruses. Over the last five years, coxsackievirus A6 has been identified as a causative agent in outbreaks in Europe, South-East Asia and America. It has an atypical presentation compared with other enteroviruses, with more widespread rash, larger blisters and subsequent skin peeling and/or nail shedding.

Are new place representations independent of theta and path integration?

Brandon et al. (2014) show that the formation of place cell representations in new environments is preserved under septal inactivation, and is thus likely independent of the hippocampal theta rhythm and, by implication, the firing of entorhinal grid cells and the process of path integration.