Publications by authors named "Hayley McCullough"

Article Synopsis
  • Fibromyalgia syndrome (FMS) is a prevalent chronic pain condition, and recent research highlights the potential involvement of serum immunoglobulin Gs (IgGs), leading to challenges in management due to a lack of clear mechanisms.
  • An international expert group conducted a multi-phase research prioritization exercise that resulted in 39 interim recommendations for future studies on FMS, emphasizing the importance of autoantibody investigation, trial design, and therapeutic interventions.
  • The process aimed to direct research towards useful applications for patients, ensuring that the findings are relevant for patients, healthcare professionals, and funding organizations interested in FMS.
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Initial evidence suggested that people with complex regional pain syndrome (CRPS) have reduced attention to the affected side of their body and the surrounding space, which might be related to pain and other clinical symptoms. Three previous unblinded, uncontrolled studies showed pain relief after treatment with prism adaptation, an intervention that has been used to counter lateralised attention bias in brain-lesioned patients. To provide a robust test of its effectiveness for CRPS, we conducted a double-blind randomized controlled trial of prism adaptation for unilateral upper-limb CRPS-I.

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There is some evidence that people with Complex Regional Pain Syndrome (CRPS) show reduced attention to the affected relative to unaffected limb and its surrounding space, resembling hemispatial neglect after brain injury. These neuropsychological symptoms could be related to central mechanisms of pathological pain and contribute to its clinical manifestation. However, the existing evidence of changes in spatial cognition is limited and often inconsistent.

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