Publications by authors named "Hayley Lee"
Article Synopsis
- A study was conducted on early-stage breast cancer patients without diabetes who received dexamethasone alongside taxane chemotherapy from August 2017 to December 2019.
- The research found that 67% of these patients experienced steroid-induced hyperglycemia (SIH), with significant glycemic fluctuations in those reaching glucose levels above 200 mg/dL.
- Non-Hispanic White patients had a notably higher risk for developing SIH, and over 90% of patients saw their hyperglycemia resolve after treatment, with only a small number remaining hyperglycemic post-treatment.
Objective: Immune checkpoint inhibitors (ICIs) perturb T-cell regulatory pathways to enhance antitumor immunity. However, an increase reporting of ICI-associated diabetes is observed in adults. To our knowledge, no cases have been reported in the pediatric population.
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