Publications by authors named "Hayley Leake"

Introduction: The effect of pain education (PE) on pain intensity and function diminishes after a few months in people with chronic low back pain (CLBP). One possible explanation is the return of underlying fears and worries related to the condition.

Objective: To explore topics related to participants' beliefs and feelings that might explain why fears and worries persist after a PE-grounded intervention for CLBP.

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Pain science education (PSE) is an important component of pediatric pain care; however, access to services is limited. To disseminate pain science concepts on social media, we partnered with adolescents with chronic pain to codesign content. We engaged 7 adolescent codesigners (aged 13-18 years) with lived experience of chronic pain to take part in 4 codesign workshops.

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Pain science education (PSE) provides people with an understanding of "how pain works" grounded in the biopsychosocial model of pain; it has been demonstrated to improve outcomes in musculoskeletal pain conditions. Preliminary evidence suggests PSE may be effective for female individuals with persistent pelvic pain, but how the content of PSE needs to be modified for this group remains to be determined. A reflexive thematic analysis of qualitative data was performed to identify PSE concepts that female individuals with persistent pelvic pain consider important and why.

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Article Synopsis
  • Patient education is very important for helping women who have ongoing pelvic pain, but there are many different ways to teach them, and it's not clear which is the best.
  • A review looked at different guidelines from healthcare experts about managing pelvic pain in women and found 17 useful guidelines after checking through over 3,000 records.
  • Most of these guidelines said that patient education is needed, focusing on treatment options and understanding the pain, but they suggested different ways to teach, like support groups and printed materials.
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Since it emerged in the early 2000's, intensive education about 'how pain works', widely known as pain neuroscience education or explaining pain, has evolved into a new educational approach, with new content and new strategies. The substantial differences from the original have led the PETAL collaboration to call the current iteration 'Pain Science Education'. This review presents a brief historical context for Pain Science Education, the clinical trials, consumer perspective, and real-world clinical data that have pushed the field to update both content and method.

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Article Synopsis
  • The study aimed to identify the barriers and facilitators faced by authors of randomized controlled trials in sports and exercise medicine when using intervention reporting guidelines (CERT and TIDieR) through an online survey.
  • A total of 84 authors from 21 countries participated, revealing 8 themes that categorized barriers (like publication constraints and low awareness) and facilitators (such as journal requirements and peer recommendations).
  • The research suggests that most barriers are changeable and could be improved by journals enforcing guideline use and implementing educational initiatives for researchers.
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Background: The Sensation and Pain Rating Scale (SPARS) allows rating of non-painful as well as painful percepts. While it performs well in the experimental context, its clinical utility is untested. This prospective, repeated-measures study mixed qualitative and quantitative methods to examine the utility and performance of the SPARS in a clinical context, and to compare it with the widely used 11-point NRS for pain.

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Objective: To evaluate the comparative effectiveness and safety of analgesic medicines for acute non-specific low back pain.

Design: Systematic review and network meta-analysis.

Data Sources: Medline, PubMed, Embase, CINAHL, CENTRAL, ClinicalTrials.

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Explaining chronic pain to children and families can be challenging, particularly in the absence of an obvious physiologically identifiable cause for the child's pain. In addition to medical intervention, children and families may expect clinicians to provide clarity around the cause of pain. Such explanations are often provided by clinicians who have not received formal pain training.

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A new wave of treatments has emerged to target nervous system alterations and maladaptive conceptualizations about pain for chronic low back pain. The acceptability of these treatments is still uncertain. We conducted a qualitative study alongside a randomized controlled trial to identify perceptions of facilitators or barriers to participation in a non-pharmacological intervention that resulted in clinically meaningful reductions across 12 months for disability compared to a sham intervention.

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Background: Pain science education (PSE) is commonly integrated into treatments for childhood-onset chronic pain. A core component of PSE is learning about, and often reconceptualizing, the biology of chronic pain. Yet, few interventions have been developed specifically for young adults and little is known about how young adults conceptualize the biology of pain.

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Introduction: Low back pain contributes to an increasing global health burden exacerbated by unsustained improvements from current treatments. There is a need to develop, and test interventions to maintain initial improvements from low back pain treatments. One option is to implement a booster intervention.

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Over the last decade, the content, delivery and media of pain education have been adjusted in line with scientific discovery in pain and educational sciences, and in line with consumer perspectives. This paper describes a decade-long process of exploring consumer perspectives on pain science education concepts to inform clinician-derived educational updates (undertaken by the authors). Data were collected as part of a quality audit via a series of online surveys in which consent (non-specific) was obtained from consumers for their data to be used in published research.

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Article Synopsis
  • Self-management is important for women with endometriosis, who often rely on various strategies to cope with their symptoms; however, the effectiveness of these strategies is unclear.
  • A systematic review was conducted, analyzing studies on self-management strategies like dietary supplements and exercise, but most showed high risk of bias and lack of effectiveness compared to standard treatments.
  • The review highlights the need for more rigorous research to properly evaluate and recommend self-management strategies for managing endometriosis symptoms.
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Article Synopsis
  • - The study investigates the treatment recommendations for persistent pelvic pain (PPP) in females, highlighting inconsistencies despite existing clinical practice guidelines (CPGs) aimed at standardizing care.
  • - Researchers evaluated 20 CPGs, identifying a total of 270 recommendations with high quality ratings in certain areas, though there was variability in recommendations for psychological and conservative treatments.
  • - Four specific guidelines were recommended for best practices related to conditions like endometriosis and polycystic ovary syndrome, with a notable emphasis on pharmaceutical and surgical interventions.
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Objectives: This meta-analysis aims to investigate the efficacy and safety of medicines that target neurotrophic factors for low back pain (LBP) or sciatica.

Methods: We searched published and trial registry reports of randomized controlled trials evaluating the effect of medicines that target neurotrophic factors to LBP or sciatica in seven databases from inception to December 2020. Two reviewers independently identified studies, extracted data, and assessed the risk of bias and certainty in the evidence.

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Letter to the Editor-in-Chief in response to article "Education With Therapeutic Alliance Did Not Improve Symptoms in Patients With Chronic Low Back Pain and Low Risk of Poor Prognosis Compared to Education Without Therapeutic Alliance: A Randomized Controlled Trial" by Miyamoto et al..

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Background: Resistance training is the gold standard exercise mode for accrual of lean muscle mass, but the isolated effect of resistance training on body fat is unknown.

Objectives: This systematic review and meta-analysis evaluated resistance training for body composition outcomes in healthy adults. Our primary outcome was body fat percentage; secondary outcomes were body fat mass and visceral fat.

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Background: Changes in body composition during cancer treatments have been linked with poorer outcomes, and increased morbidity and mortality. The effect of resistance training (RT) on body composition in cancer cohorts is debated.

Objective: We conducted a systematic review and meta-analysis to determine the effect of RT on body composition during and after treatment.

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Objective: To investigate the efficacy, acceptability, and safety of muscle relaxants for low back pain.

Design: Systematic review and meta-analysis of randomised controlled trials.

Data Sources: Medline, Embase, CINAHL, CENTRAL, ClinicalTrials.

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Objective: Low back pain is the leading contributor to the global disability burden. The Global Spine Care Initiative (GSCI) recommend patient-centred care to stem the cost of low back pain. One way to enhance patient-centred care is by better understanding what is relevant for people with low back pain.

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