Publications by authors named "Hayley Glantz"
Article Synopsis
- To prevent HIV-1 transmission, high levels of broadly neutralizing antibodies are necessary at mucosal sites of exposure, particularly in the colorectal and genitourinary tracts.
- A study compared the biodistribution of two monoclonal antibodies, VRC01 and its longer-lasting variant VRC01LS, over 1-52 weeks post-infusion, finding VRC01LS levels significantly higher in various tissues at earlier and later time points.
- While both antibodies are mainly retained in rectal and cervical tissue, only a small percentage reaches seminal and rectal secretions; VRC01LS shows a longer elimination half-life, indicating its potential for sustained protection against HIV-1.
Emerging SARS-CoV-2 variants have raised concerns about resistance to neutralizing antibodies elicited by previous infection or vaccination. We examined whether sera from recovered and naïve donors collected prior to, and following immunizations with existing mRNA vaccines, could neutralize the Wuhan-Hu-1 and B.1.
View Article and Find Full Text PDFEmerging SARS-CoV-2 variants have raised concerns about resistance to neutralizing antibodies elicited by previous infection or vaccination. We examined whether sera from recovered and naive donors collected prior to, and following immunizations with existing mRNA vaccines, could neutralize the Wuhan-Hu-1 and B.1.
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