Exosomes in Cosmetic Dermatology: A Review of Benefits and Challenges.

Background: Exosomes are small extracellular vesicles (30-150 nm in size) that play a critical role in cellular communication, transporting proteins, lipids, and nucleic acids between cells. This literature review focuses on evaluating the potential benefits and limitations of exosomes in enhancing skin health and aesthetics through indications such as skin rejuvenation, hair restoration, and pigmentation disorders.

Methods: A thorough literature search was conducted on PubMed using specific MeSH, including "exosomes," "aesthetics," "cosmetic dermatology," "skin rejuvenation," "hair growth," and "wrinkle reduction.

Leveraging Single Nucleotide Polymorphism Profiling for Precision Skin Care: How SNPs Shape Individual Responses in Cosmetic Dermatology.

Introduction: Single-nucleotide polymorphisms (SNPs) represent a significant genetic variation influencing individual responses to cosmetic dermatology treatments. SNP profiling offers a pathway to personalized skincare by enabling practitioners to predict patient outcomes, customize interventions, and mitigate risks.

Background: The integration of genetic insights into dermatology has gained traction, with SNP analysis revealing predispositions in skin characteristics, such as collagen degradation, pigmentation, and inflammatory responses.

Vertex Augmentation With Hyaluronic Acid Filler: A Novel Technique for Height Enhancement and Cephalic Contouring.

Height augmentation and cephalic contouring using hyaluronic acid (HA) fillers represent an innovative approach in minimally invasive aesthetic medicine. This study introduces a novel technique for vertex augmentation, leveraging cross-linked HA fillers to achieve subtle height enhancement and cephalic contouring. A 42-year-old male patient seeking non-surgical height augmentation underwent vertex injections with 15 ml of HA filler (e.

The Role of GLP-1 Agonists in Esthetic Medicine: Exploring the Impact of Semaglutide on Body Contouring and Skin Health.

Introduction: Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide, have revolutionized the treatment of diabetes and obesity by promoting significant weight loss through incretin effects. However, rapid weight reduction induced by these medications often leads to esthetic challenges, including facial volume loss, skin laxity, and body contour irregularities. This commentary reviews the esthetic consequences of GLP-1-induced weight loss and explores solutions for managing these concerns in clinical practice.

The Transformative Potential of AI in Ultrasound for Facial Aesthetics.

Background: The integration of artificial intelligence (AI) and ultrasound (US) technology is reshaping facial aesthetics, providing enhanced diagnostic precision, procedural safety, and personalized patient care. The variability in US imaging, stemming from patient anatomy, operator skills, and equipment diversity, poses challenges in achieving consistent and accurate outcomes. AI addresses these limitations by standardizing imaging protocols, automating image analysis, and supporting real-time decision-making.

A Psychosocial Exploration of Augmented Reality and Virtual Reality Apps in Cosmetic Procedures.

Background: The integration of augmented reality (AR) and virtual reality (VR) technologies into cosmetic dermatology offers new avenues for enhancing patient engagement, satisfaction, and decision-making. These immersive tools allow patients to better visualize the outcomes of procedures before treatment, improving communication with physicians and increasing confidence in cosmetic interventions. Despite the promise these technologies hold, there remain concerns regarding their accessibility, technical limitations, ethical challenges, and the potential for algorithmic bias.

Manufacturing Process of Hyaluronic Acid Dermal Fillers.

Hyaluronic acid (HA) fillers are extensively utilized in aesthetic medicine due to their biocompatibility, reversibility, and effectiveness in enhancing skin hydration, volume, and overall appearance. These fillers are predominantly produced through microbial fermentation, followed by a critical cross-linking process that enhances their longevity by resisting enzymatic degradation. This review provides a thorough examination of the manufacturing processes that differentiate HA fillers, with particular attention to the distinctions between biphasic and monophasic variants.

Dermatological Health in the Light of Skin Microbiome Evolution.

Background: The complex ecosystem of the skin microbiome is essential for skin health by acting as a primary defense against infections, regulating immune responses, and maintaining barrier integrity. This literature review aims to consolidate existing information on the skin microbiome, focusing on its composition, functionality, importance, and its impact on skin aging.

Methods: An exhaustive exploration of scholarly literature was performed utilizing electronic databases including PubMed, Google Scholar, and ResearchGate, focusing on studies published between 2011 and 2024.

Hyaluronan Hybrid Cooperative Complexes Injection as a Biostimulation for Postobese Skin Laxity in the Arm: A Histopathologic Study.

Background: The Hybrid Cooperative Complexes of high and low molecular weight hyaluronic acids (HHCC) improve skin structure and bioactivity. Massive weight loss damages cellular composition and morphological structure of skin. An injective treatment of postobese skin consisting of HHCC may have a role in counteracting these histopathological alterations.

Educational strategies to combat harmful cosmetic dermatology trends in Generations Alpha and Z.

This contribution argues in favor of implementing comprehensive educational strategies to combat the harmful effects of social media (SM) on body image and self-perception among Generations Alpha and Z. These generations are often exposed to unattainable beauty standards that can lead to distorted self-perceptions and body image disorders such as Zoom dysmorphia. To address this issue, we propose embedding health education, critical media literacy, and active parental involvement in educational curricula.

The relevance and accuracy of an AI algorithm-based descriptor on 23 facial attributes in a diverse female US population.

Background: The response of AI in situations that mimic real life scenarios is poorly explored in populations of high diversity.

Objective: To assess the accuracy and validate the relevance of an automated, algorithm-based analysis geared toward facial attributes devoted to the adornment routines of women.

Methods: In a cross-sectional study, two diversified groups presenting similar distributions such as age, ancestry, skin phototype, and geographical location was created from the selfie images of 1041 female in a US population.

Exploring the landscape of AI adoption in cosmetic medicine and surgery: Insights from the 25th IMCAS Congress (International Master Course in Aging Science).

Introduction: The integration of artificial intelligence (AI) into cosmetic medicine promises to revolutionize the field by enhancing diagnosis, treatment planning, and patient care.

Objective: This manuscript explores the current adoption and perceptions of AI among professionals in the realm of cosmetic dermatology and plastic surgery, utilizing insights from the IMCAS Congress 2024 attendees.

Methods: A survey employing a digital questionnaire with 14 questions was distributed among attendees of the IMCAS Congress 2024 to evaluate their familiarity with AI, usage in clinical practice, perceived advantages, and concerns regarding data privacy and security.

Picosecond lasers in cosmetic dermatology: where are we now? An overview of types and indications.

Q-switched lasers have undeniably revolutionized the field of laser dermatology since four decades ago. Just as the first-generation laser emits its photonic signal in a few nanoseconds, the picosecond laser delivers pulse widths of at least ten times shorter. These devices offer a powerful tool for treating a wide range of skin conditions with a minimal downtime for visible improvement.

Cross-cultural perspectives on patient expectations in cosmetic dermatology: A comparative analysis across countries and ethnicities.

Patient expectations in cosmetic dermatology exhibit significant variations across countries, cultures, and ethnicities, thereby reflecting individual desires, concerns, and goals. While some individuals seek aesthetic enhancements, others prioritize addressing specific skin conditions within the context of beauty norms in their respective countries. The provision of personalized and culturally sensitive care plays a crucial role in meeting these diverse expectations.