Publications by authors named "Hayek A"
Rethinking Thrombus Aspiration in STEMI: Balancing Efficacy and Risk.
JACC Cardiovasc Interv
December 2024
Background: Managing glycemia during Ramadan is challenging for individuals with type 1 diabetes (T1D) due to prolonged fasting and altered eating patterns. While many are exempt from fasting, some choose to fast, necessitating careful monitoring. The glycemia risk index (GRI) is valuable for assessing glycemic quality and interpreting continuous glucose monitoring (CGM) data to identify individuals needing closer clinical attention.
View Article and Find Full Text PDFNeurologic Events After TAVR: Inevitable, Predictable, or Reducible?
JACC Cardiovasc Interv
November 2024
Article Synopsis
- RANTES (CCL5) is a chemokine involved in immune response and may play a role in diseases like atherosclerosis, but its importance during acute myocardial infarction (MI) is not well understood.
- The study analyzed 250 patients with ST-segment-elevation MI, tracking serum levels of RANTES over time and its correlation with major adverse cardiovascular events during a 12-month follow-up.
- Results showed that lower levels of RANTES were linked to a higher risk of major adverse cardiovascular events, suggesting that post-MI RANTES levels could serve as a useful prognostic marker for patients.
Background: This study assessed glucometric changes in Type 2 diabetes mellitus (T2DM) patients before, during, and after Ramadan fasting using an intermittently scanned continuous glucose monitoring system (isCGMS).
Methods: This prospective comparative study included T2DM patients aged 30-70 years who were receiving nonintensive insulin in Riyadh, Saudi Arabia. In addition to the baseline characteristics, glycated hemoglobin (HbA1c) and ambulatory glucose profile (AGP)-derived metric data were collected at three specific points: pre-, during-, and post-Ramadan.
Background: Ongoing debate remains regarding optimal antithrombotic therapy in patients with atrial fibrillation (AF) and coronary artery disease.
Methods: We performed a systematic review and meta-analysis to synthesize randomized controlled trials (RCTs) comparing the following: (i) dual-pathway therapy (DPT; oral anticoagulant [OAC] plus antiplatelet) vs triple therapy (OAC and dual-antiplatelet therapy) after percutaneous coronary intervention (PCI) or acute coronary syndrome (ACS), and (iii) OAC monotherapy vs DPT at least 1 year after PCI or ACS. Following a 2-stage process, we identified systematic reviews published between 2019 and 2022 on these 2 clinical questions, and we updated the most comprehensive search for additional RCTs published up to October 2022.
The coronary angiogram is the gold standard for evaluating the severity of coronary artery disease stenoses. Presently, the assessment is conducted visually by cardiologists, a method that lacks standardization. This study introduces DeepCoro, a ground-breaking AI-driven pipeline that integrates advanced vessel tracking and a video-based Swin3D model that was trained and validated on a dataset comprised of 182,418 coronary angiography videos spanning 5 years.
View Article and Find Full Text PDFIntroduction: Healthcare professionals' awareness of adverse drug reaction reporting and pharmacovigilance practices differ by country. The study assesses healthcare professionals' knowledge, practice, and potential barriers to pharmacovigilance-related practices and reporting adverse drug reaction.
Methods: A cross-sectional investigation was conducted in government and private healthcare settings.
Background: Diabetes technology in the form of digital health or medical devices holds a promise for improving the quality of life and glycemic outcomes. A comprehensive insight into diabetes technology and its impact in Saudi Arabia and the MENA region may improve type 1 diabetes mellitus (T1DM) management.
Objective: This study aimed to assess the impact of different DM-specific technologies: insulin pump therapy, continuous glucose monitoring (CGM), and automated insulin delivery system in terms of glycemic control and QoL among T1DM patients in Saudi Arabia and the MENA region.
Transcatheter aortic valve replacement (TAVR) has emerged as a viable treatment for aortic valve disease, including low-risk patients. However, as TAVR usage increases, concerns about long-term durability and the potential for addition interventions have arisen. Transcatheter aortic valve (TAV)-in-TAV procedures have shown promise in selected patients in numerous registries, offering a less morbid alternative to TAVR explantation.
View Article and Find Full Text PDFBackground And Aims: To examine the influence of school life in children and adolescents with type 1 diabetes (T1D) by comparing the glycemic control and Ambulatory Glucose Profile (AGP) between the holidays and schooldays.
Methods: This is a retrospective study conducted on 147 patients with T1D (14-19 years) who used an intermittently scanned Continuous Glucose Monitoring (isCGM) system to self-test their glucose levels during the periods of school time and holiday time. A record was maintained of the Continuous Glucose Monitoring (CGM) metrics i.
Article Synopsis
- Re-POT (proximal optimization technique) is a new method for treating coronary bifurcation lesions, showing better artery outcomes compared to traditional techniques, and has proven good short-term results.
- The CABRIOLET registry studied the long-term benefits of the Re-POT method in a diverse group of 500 patients across five European centers, focusing on complications like target lesion failure over a year.
- Results indicated a low rate of target lesion failure (2.0%) and target lesion revascularization (1.6%) after one year, suggesting that the Re-POT technique is a safe and effective option for patients with various types of bifurcation lesions.
Article Synopsis
- The study assessed metabolic control, gluten-free diet adherence, and quality of life in type 1 diabetes and celiac disease patients.
- Data was collected from medical records and assessments included HbA1c, the Celiac Dietary Adherence Test, and a quality of life survey.
- Results showed no significant link between diet adherence and metabolic control or quality of life, indicating a need for more research on the diet's effects.
Background And Aims: This study aims to assess patient-reported satisfaction and metabolic outcomes following the initiation of the second generation of the Freestyle Libre 2 (FSL2) system in patients with type 1 diabetes (T1D).
Methods: This non-randomized single-arm observation study was conducted on 86 patients with T1D living in Saudi Arabia, who were asked to wear the FSL2 for 12 weeks. The demographic data were collected at baseline, while the continuous glucose monitoring (CGM) metrics were gathered, i.
Objective: There is still uncertainty about the management of patients with pheochromocytoma-induced cardiogenic shock (PICS). This study aims to investigate the clinical presentation, management, and outcome of patients with PICS.
Methods: We collected, retrospectively, the data of 18 patients without previously known pheochromocytoma admitted to 8 European hospitals with a diagnosis of PICS.
Article Synopsis
- Continuous glucose monitoring (CGM) devices like the Freestyle Libre™ help manage glucose levels in patients with type 2 diabetes by converting glucose data into estimated HbA1c values.
- A study reviewed data from 93 patients using these devices for one year, focusing on glycemic markers and the relationship between HbA1c and CGM results.
- Results showed that HbA1c levels significantly decreased with continued use of the device and there were strong correlations between the lab-derived HbA1c and CGM values over time.
Article Synopsis
- Management of thrombus during primary percutaneous coronary intervention (pPCI) is crucial to prevent complications like stent malapposition, especially at coronary bifurcations, leading to the development of a new experimental model to study thrombus behavior.
- In the study, three pPCI strategies were tested on a bifurcation model using human blood to analyze their effects on thrombus trapping and embolization: balloon-expandable stent (BES), BES with proximal optimizing technique (POT), and nitinol self-apposing stent (SAS).
- Results showed that while BES trapped more thrombus than SAS or BES+POT, both SAS and BES+POT provided significantly better stent apposition, suggesting that
Background: Ventricular septal rupture (VSR) is an uncommon but life-threatening complication of acute myocardial infarction. Extra corporeal life support (ECLS) use in the preoperative setting allows hemodynamic stabilization for a delayed surgery. We aimed to assess the role of ECLS in the preoperative period of post infarction VSR surgery.
View Article and Find Full Text PDFIntroduction The main objective of the current study was to perform a comparison of point-of-care testing for hemoglobin A1c (POCT-HbA1c) versus the standard laboratory method (Lab HbA1c) and their relationship to time-in-range (TIR) and glucose variability (GV) among patients with diabetes mellitus (DM) presented to the outpatient diabetes clinics. Methods This single-center cross-sectional study was carried out on diabetic patients (aged ≥14 years of both genders) who undergo routine follow-up at our institution and whose physicians ordered HbA1c analysis for routine care. The included patients were those using the intermittently scanned continuous glucose monitoring (isCGM) Abbott's FreeStyle Libre system for at least three months and regular CGM users with at least 70% use.
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