Curcumin induced photodynamic therapy mediated suppression of quorum sensing pathway of Pseudomonas aeruginosa: An approach to inhibit biofilm in vitro.

Objective: The objective of this study was to inhibit the Pseudomonas aeruginosa biofilm through curcumin-mediated antimicrobial photodynamic therapy (A-PDT).

Background: The mechanism behind A-PDT mediated photoinactivation depend upon reactive oxygen species (ROS) production, like singlet oxygen and free radicals.

Methods: To evaluate the antibacterial efficacy of curcumin induced A-PDT on P.

Photodynamic efficacy of toluidine blue O against mono species and dual species bacterial biofilm.

Aim: The purpose of this study was to investigate how Enterococcus faecalis and Streptococcus mutans behave in mono and dual species biofilm after photodynamic treatment.

Background: Antimicrobial photodynamic therapy (aPDT) leads to the generation of reactive oxygen species (ROS) that destroys bacterial cells in presence of a photosensitizer, visible light, and oxygen.

Material And Methods: We have taken Enterococcus faecalis and Streptococcus mutans as monospecies culture and their dualspecies culture biofilm.