Publications by authors named "Hayato Toma"

Objective: Sarcopenia and osteoporosis substantially influence health and lifespan. However, the variables affecting skeletal muscle mass (SMM) or bone mineral density (BMD) remain unknown.

Design And Methods: From August 1, 2018 to July 31, 2019, we conducted a single-center, observational cohort study with 291 Japanese adult patients on maintenance hemodialysis due to end-stage kidney disease, who had their femoral neck BMD measured using dual-energy X-ray absorptiometry.

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Article Synopsis
  • - A 75-year-old man on hemodialysis for diabetic nephropathy developed pancytopenia after starting polaprezinc for low zinc levels and dysgeusia, even after stopping the medication.
  • - Lab tests showed low white blood cell, hemoglobin, and platelet counts, alongside abnormal bone marrow findings and elevated WT1 mRNA levels.
  • - Further investigation revealed low copper levels indicating zinc-induced copper deficiency, and treatment with cocoa (high in copper) improved his blood counts and bone marrow condition, highlighting the risks of zinc supplementation in patients with chronic kidney disease.
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