Publications by authors named "Hayato Honjo"
Appl Environ Microbiol
June 2024
Article Synopsis
- Resistance to potassium tellurite (PT) is crucial for isolating Shiga toxin-producing E. coli (STEC) O157:H7, and a study identified an O157:H7 strain that resists PT despite lacking the common resistance gene cluster.
- Whole-genome sequencing revealed a nonsynonymous mutation in a different PT resistance gene, which was found to enhance PT resistance by increasing the expression of this gene through a change in its internal promoter.
- This research indicates that even strains without the typical resistance genes can achieve PT resistance due to single mutations, highlighting the adaptability of STEC in various environments.
