Synopsis of recent research by authors named "Hayat Mokrani"
- Hayat Mokrani's recent research encompasses the investigation of endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome, highlighting the relationship between acute pulmonary hypertension and mortality in affected individuals.
- In the study of acute myeloid leukaemia (AML), Mokrani explores the genetic hierarchy and temporal variegation of clonal histories, identifying critical pre-leukaemic lesions and various mutations associated with the disease's onset and relapse.
- Mokrani's work also includes insights into the regulation of megakaryocyte proplatelet formation by the formin DIAPH1, revealing its role in cytoskeletal remodeling, as well as examining the impact of TET2 mutations on erythroid and granulomonocytic differentiation in human hematopoietic progenitors.
