Publications by authors named "Haya Al-Dusery"
Article Synopsis
- Juvenile idiopathic arthritis (JIA) is a complex and poorly understood condition thought to have genetic influences, characterized by a variety of arthritis types with an unknown origin.
- *The study focused on 43 patients with LACC1-associated juvenile arthritis, identifying genetic variants and providing clinical details, including a high prevalence of early onset disease and aggressive treatment responses.
- *Results showed that a significant portion of patients exhibited severe forms of arthritis and poor treatment outcomes, expanding the understanding of LACC1's role in JIA pathology.
Background: Molecular genetics techniques are an essential diagnostic tool for primary immunodeficiency diseases (PIDs). The use of next-generation sequencing (NGS) provides a comprehensive way of concurrently screening a large number of PID genes. However, its validity and cost-effectiveness require verification.
View Article and Find Full Text PDFObjective: The pathologic basis of systemic juvenile idiopathic arthritis (JIA) is a subject of some controversy, with evidence for both autoimmune and autoinflammatory etiologies. Several monogenic autoinflammatory disorders have been described, but thus far, systemic JIA has only been attributed to a mutation of MEFV in rare cases and has been weakly associated with the HLA class II locus. This study was undertaken to identify the cause of an autosomal-recessive form of systemic JIA.
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