Publications by authors named "Hauschild M"

This scoping review examines environmental impacts related to food production and consumption in Nordic and Baltic countries. The overarching advice to all Nordic and Baltic countries, in line with the current body of scientific literature, is to shift to a more plant-based dietary pattern and avoid food waste. Taking into account current consumption patterns, there is a high potential and necessity to shift food consumption across the countries to minimise its environmental impact.

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Background: Buprenorphine is a first-line treatment for opioid use disorder (OUD), essential for reducing opioid overdose mortality and improving treatment retention. Despite federal policies that mandate the acceptance of buprenorphine in recovery residences, individuals in South Florida taking this medication often face significant barriers to admission. This study uses a secret shopper survey to examine whether federal policies regarding prescribed buprenorphine use are being violated in South Florida recovery residences.

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  • The study aimed to identify transportation barriers faced by pediatric patients traveling to a major orthopaedic center and their impact on care, along with potential solutions.
  • A survey was conducted with caregivers of patients, analyzing factors like socioeconomic status, transportation methods, and scheduling, revealing that 13% missed appointments due to transport issues.
  • Key findings showed that longer travel times, difficult scheduling, and certain patient conditions (like nonambulatory status) significantly increased the likelihood of missed visits, suggesting the need for better accessibility and streamlined scheduling options.
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Background: Xylazine is an increasingly common adulterant in the North American unregulated drug supply that is associated with adverse health outcomes (e.g., skin infections, overdose).

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Background: Xylazine is an increasingly common adulterant in the North American unregulated drug supply that is associated with adverse health outcomes (e.g., skin infections, overdose).

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Background: Femoral fractures in children have the highest probability for abuse after skull fractures and humeral shaft fractures. However, the reported proportion of pediatric femur fractures that result from nonaccidental trauma (NAT) varies in the literature from 2% to 60%. The purpose of this study was to determine the patient characteristics associated with a physician's decision to conduct a NAT workup and challenge universal clinical practice guidelines stating that all children younger than 3 years with a diaphyseal femur fracture be evaluated for NAT.

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Ecotoxicological impacts of chemicals released into the environment are characterized by combining fate, exposure, and effects. For characterizing effects, species sensitivity distributions (SSDs) estimate toxic pressures of chemicals as the potentially affected fraction of species. Life cycle assessment (LCA) uses SSDs to identify products with lowest ecotoxicological impacts.

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  • The study focused on the unique psychosocial challenges faced by children with congenital upper limb differences (CULD) and their caregivers, aiming to identify their needs for developing a supportive group curriculum.
  • Researchers included 14 caregivers (13 mothers, 1 father) of children aged 3 months to 14 years, using surveys and interviews to gather data on their experiences and challenges.
  • Results showed average scores in peer relationships and pain interference, but lower scores in physical function, while caregivers expressed strong interest in group support addressing topics like social skills, self-confidence, and advocacy for their children.
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  • - Xylazine, an alpha-2 adrenergic agonist, has become a contaminant in fentanyl and is associated with naloxone-resistant overdoses and unusual wounds in drug users; a unique case in Florida involved a woman with xylazine-induced wounds confirmed through a test strip at a syringe services program.
  • - The woman, 43, presented to a student-run clinic for care of multiple ulcerations on her forearms, and after receiving treatment, she returned seven weeks later with worsening wounds; xylazine was confirmed in her urine during this second visit.
  • - Many people who use drugs (PWUD) struggle to access traditional healthcare due to stigma and lack of insurance, highlighting the urgent need for improved access
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  • A study conducted at a student-run clinic in Miami found that 55.9% of patients who inject drugs tested positive for xylazine in their urine samples.
  • The presence of xylazine was linked to factors such as unsheltered homelessness, wounds, and positive tests for hepatitis C, fentanyl, and MDMA.
  • The findings highlight the growing prevalence of xylazine in the Southeastern U.S. and emphasize the need for better screening to address associated risks for people who inject drugs.
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  • Bridging applied ecology and ecotoxicology is crucial for ecosystem protection, as there is often a disconnect between how these fields assess environmental pressures.
  • The study introduces taxonomic-group-specific Species Sensitivity Distributions (SSDs) for algae, invertebrates, and vertebrates based on data from 180 chemicals, suggesting that these tailored assessments enhance pollution impact evaluations, especially for certain chemicals.
  • The findings propose a new framework for using split SSDs, which could significantly improve decision support in environmental protection and management of freshwater ecosystems worldwide.
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Assessing the prospective climate preservation potential of novel, innovative, but immature chemical production techniques is limited by the high number of process synthesis options and the lack of reliable, high-throughput quantitative sustainability pre-screening methods. This study presents the sequential use of data-driven hybrid prediction (ANN-RSM-DOM) to streamline waste-to-dimethyl ether (DME) upcycling using a set of sustainability criteria. Artificial neural networks (ANNs) are developed to generate waste valorization experimental results and model the operating space of biorefineries applying the organic fraction of municipal solid waste (OFMSW) and sewage sludge (SS).

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Introduction: Turner syndrome association with multi-organ system comorbidities highlights the need for effective implementation of follow-up guidelines. We aimed to assess the adequacy of care with international guidelines published in 2007 and 2017 and to describe the phenotype of patients.

Methods: In this multicenter retrospective descriptive cohort study, we collected growth and pubertal parameters, associated comorbidities, treatment, and karyotype in patients diagnosed at age <18 years between 1993 and 2022.

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Article Synopsis
  • - Xylazine, an alpha-2 adrenergic receptor agonist, is increasingly found in fentanyl, causing naloxone-resistant overdoses and chronic wounds in people who inject drugs (PWID), as highlighted in a unique case study in Florida.
  • - A 43-year-old woman with severe opioid and stimulant use disorders presented with worsening ulcerations on her forearms at a syringe services program (SSP), where xylazine was confirmed in her urine using a test strip.
  • - The case underscores the critical need for accessible healthcare for PWID, particularly around xylazine-related issues, and emphasizes the importance of developing guidelines for treating related wounds, as many do not seek traditional healthcare due to barriers. *
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Background: Metabolic programming of glucose homeostasis in the first 1,000 days of life may impact lifelong metabolic and cardiovascular health. Continuous glucose monitoring (CGM) devices may help measure the impact of dietary intake on glucose rhythms and metabolism in infants during the complementary feeding period.

Objectives: Demonstrate the feasibility of CGM to measure and quantify glucose variability in response to infant feeding and to evaluate associations between macronutrient meal composition and glucose variability.

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Purpose: Extensive agriculture activities for crop production have led to increasing environmental impacts that threaten to exceed environmentally safe limits. The purpose of this study is to analyze resource efficiency of the agri-food industry, considering the case of sugarcane production in Pakistan.

Methods: A holistic approach has been applied by determining the relevant impact categories and Sustainable Development Goals (SDGs), and linking them with Planetary Boundary-based Life Cycle Assessment (PB-LCA).

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The attachment of silver(I) cations to 5,7,12,14-tetraphenyl-6,13-diazapentacene and its reduced dihydro-form has been studied by electrospray ionization mass spectrometry (ESI-MS). The structure elucidation of the Ag complexes has been accomplished in gas-phase collision experiments in conjunction with density functional theory (DFT) calculations. The oxidized form provides a favourable cavity for the Ag ion, leading to the [1 : 1] complex with the highest resilience towards dissociation and severely hindering the attainment of a second molecular ligand.

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Purpose: The aim of this study was the evaluation of pain, function, and overall satisfaction after total hip arthroplasty (THA) using three different standard surgical approaches (DAA (direct anterior approach), lateral, and posterior approach) 2 years postoperatively. Additionally, we compared the results with recently published results of the same study population 6 weeks postoperatively.

Methods: In a multisurgeon, prospective, single-center cohort study, a total of initial 188 patients who underwent total hip arthroplasty (THA) between February 2019 and April 2019 were analyzed on pain, function, and satisfaction within the first days, 6 weeks, and 2 years postoperatively according to three different approaches (DAA, lateral, and posterior approach).

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Balancing human communities' and ecosystems' need for freshwater is one of the major challenges of the 21 century as population growth and improved living conditions put increasing pressure on freshwater resources. While frameworks to assess the environmental impacts of freshwater consumption have been proposed at the regional scale, an operational method to evaluate the consequences of consumption on different compartments of the water system and account for their interdependence is missing at the global scale. Here, we develop depletion factors that simultaneously quantify the effects of water consumption on streamflow, groundwater storage, soil moisture, and evapotranspiration globally.

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Obesity is a chronical disease, which leads to multiple short- and long-term complications. 4% of Swiss children and adolescents are obese. A prompt diagnosis and multicomponent lifestyle intervention is mandatory to avoid persistence of the disease into adulthood.

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Diabetes mellitus in children is subdivided into several categories depending on the underlying pathological mechanism. Type 1 diabetes is due to the autoimmune destruction of pancreatic beta-cells, type 2 diabetes to progressive impairment in insulin secretion or insulin sensitivity, and monogenic diabetes due to genetic abnormalities, impairing insulin secretion. In monogenic diabetes, genetic defects result in pancreatic or beta-cell defects (abnormal function or destruction), resulting in neonatal or MODY (Maturity-Onset Diabetes of the Young) diabetes, depending on the age of onset.

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Several water footprint indicators have been developed to curb freshwater stress. Volumetric footprints support water allocation decisions and strive to increase water productivity in all sectors. In contrast, impact-oriented footprints are used to minimize the impacts of water use on human health, ecosystems, and freshwater resources.

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Background: Relapse rates of clubfoot deformity after initial correction range between 19% and 68% regardless of treatment approach. Most studies focus on relapse before age 4. Little research has focused on late clubfoot relapse.

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Article Synopsis
  • * Current methods lack a systematic way to connect ecotoxicity data with real-world impacts on species diversity, functional diversity, and ecosystem services, particularly in tools like life cycle assessment (LCA).
  • * The authors propose a framework to link ecotoxicity effects to ecosystem damage, outlining potential methods for connecting species loss and functional diversity to quantifying ecosystem service impacts, while discussing the strengths and limitations of each approach.
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Background: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Design: Cross-sectional pilot study conducted in the paediatric obesity unit of the Lausanne university hospital, Switzerland.

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