Synthesis of ruthenium carbonyl complexes with phosphine or substituted Cp ligands, and their activity in the catalytic deoxygenation of 1,2-propanediol.

A ruthenium hydride with a bulky tetra-substituted Cp ligand, (Cp(i)(Pr(4)))Ru(CO)(2)H (Cp(i)(Pr(4)) = C(5)(i-C(3)H(7))(4)H) was prepared from the reaction of Ru(3)(CO)(12) with 1,2,3,4-tetraisopropylcyclopentadiene. The molecular structure of (Cp(i)(Pr(4)))Ru(CO)(2)H was determined by X-ray crystallography. The ruthenium hydride complex (C(5)Bz(5))Ru(CO)(2)H (Bz = CH(2)Ph) was similarly prepared.

Portal vein thrombosis associated with coronary artery bypass surgery.

Portal vein thrombosis is a rare but well-known complication after abdominal surgery. To our knowledge, there have been no reports about this complication after cardiopulmonary bypass surgery. This can probably be explained by the variety of clinical pictures and difficulties in the establishment of a diagnosis of portal vein thrombosis.

Nonocclusive mesenteric ischemia after off-pump coronary artery bypass surgery: a word of caution.

We present a series of five cases of off-pump coronary artery bypass surgery complicated with fatal nonocclusive mesenteric ischemia. We review a total of 489 patients aged 65 and older (mean age 74.9 +/- 3.

Initial experience with the Heartstring proximal anastomotic system.

Objective: Manipulation of the aorta has been shown to be associated with postoperative neurologic events after surgical myocardial revascularization when the aorta is diseased. The Heartstring proximal anastomotic system (Guidant, Indianapolis, Ind) is a device designed to assist in the performance of proximal anastomoses with minimal aortic manipulation. We describe our initial experience with this product.

Solvent-free ketone hydrogenations catalyzed by molybdenum complexes.

Et2C=O is hydrogenated under solvent-free conditions using a catalyst prepared by hydride abstraction from HMo(CO)2[eta5:eta1-C5H4(CH2)(2)PCy2]; the catalyst functions at low catalyst loadings (< 0.4 mol%).

Long-term beneficial effect of coronary artery bypass grafting in patients with COPD.

Objective: This study assesses the impact of COPD on the long-term outcome of patients undergoing coronary artery bypass grafting (CABG).

Methods: Between 1991 and 1993, 37 patients (5.68%) undergoing CABG had significant clinical COPD.

Preoperative use of enoxaparin is not a risk factor for postoperative bleeding after coronary artery bypass surgery.

Background: The purpose of this study was to determine whether the use of low-molecular-weight heparin before coronary artery bypass surgery would be associated with an increase in bleeding and use of blood products after the operation.

Methods: Sixty-four patients (48 men and 16 women) aged 64 +/- 10 years who were undergoing primary coronary artery bypass surgery were prospectively studied. Forty-one patients were treated with either subcutaneous enoxaparin 1 mg/kg twice daily (n = 21; enoxaparin group) or intravenous heparin (n = 20; heparin group).

Detection of HPV DNA in cervical specimens collected in cytologic solution by ligation-dependent PCR.

Objective: To determine the feasibility and sensitivity of detecting human papillomavirus (HPV) in specimens collected in Cytyc PreservCyt fluid (Boxborough, Massachusetts, U.S.A.

Delayed postoperative paraplegia complicating repair of type A dissection.

We describe the very rare event of delayed transient paraplegia after repair of type A dissection of the aorta and discuss therapeutic options. We also suggest insertion of a spinal catheter as soon as there are signs or symptoms of spinal cord injury to drain spinal fluid and maximize the effect of elevated spinal cord perfusion pressure.

Metal-Catalyzed Selective Deoxygenation of Diols to Alcohols.

The internal OH group of 1,2-propanediol is selectively removed in the deoxygenation catalyzed by [{Cp*Ru(CO) } (μ-H)] OTf (1, Cp*=C Me , OTf=trifluoromethanesulfonate; see scheme). This reaction provides a model for deoxygenation of polyols derived from carbohydrates, for use in alternative, biomass-based feedstock applications. An ionic mechanism is proposed that involves the dihydrogen complex [Cp*Ru(CO) (η -H )] .

Ventricular aneurysm repair: a new approach.

Repair of chronic left ventricular aneurysm or acute rupture of the heart after myocardial infarction is associated with technical difficulties and major morbidity and mortality. We describe a new endoventricular repair for both conditions. The repair consists of externally covering a Duran ring with Dacron and internally lining it with autologous pericardium.

Phrenic nerve injury after coronary artery grafting: is it always benign?

Background: The purpose of this study was to evaluate the effect of phrenic nerve injury (PNI) occurring during coronary artery bypass grafting in patients with major chronic obstructive pulmonary disease (COPD).

Methods: Over a 42-month period, 1,303 patients underwent primary coronary artery bypass grafting. Sixty-seven (5.

Effect of systemic vasodilators on internal mammary flow during coronary bypass grafting.

Background: The effect of vasodilators on acute flow in the internal mammary (IMA) is unclear. Topical vasodilators show no effect on acute flow when the distal segment of the IMA is resected. The purpose of this study was to evaluate the effect of systemic vasodilators when this segment is resected.

The meaning of equivocal pancreatic cytology in patients thought to have pancreatic cancer.

Introduction: Fine needle aspirations (FNAs) and endoscopic retrograde cholangiopancreatography (ERCP)-guided brushings (BRUSH) are useful tools in the differentiation between malignant and benign disease of the pancreas. Once the decision to obtain a cytologic confirmation of one's clinical suspicion is made, the interpretation of the findings, especially an equivocal or negative cytology finding, can be unclear. This study seeks to evaluate the utility of cytologic studies in the evaluation of a patient with suspected pancreatic malignancy.

Chronic obstructive pulmonary disease in patients undergoing coronary artery bypass grafting.

The purpose of this study was to evaluate the effect of chronic obstructive pulmonary disease on patients undergoing coronary artery bypass grafting. Between June 1991 and June 1993, 651 patients underwent coronary artery bypass grafting: 37 patients (group I) had significant chronic obstructive pulmonary disease. These patients were compared with 37 matched control subjects (group II).

Effect of topical vasodilators on internal mammary arteries.

The internal mammary artery (IMA) is the conduit of choice for grafting the left anterior descending artery. However, arterial spasm and reduced early flow has been a cause of postoperative morbidity. The purpose of this study is to evaluate the effect of vasodilators on IMA flow.

Anatomic considerations in closed transatrial cannulation of the coronary sinus.

Successful closed transatrial coronary sinus cannulation is dependent on a proper catheter insertion site and proper catheter direction. Accurate anatomic landmarks are described to provide a reproducible cannulation site and catheter direction. This results in consistent successful cannulation of the coronary sinus.

A safe and rapid method for the mobilization of the internal mammary pedicle.

A simple method is described for the safe and rapid dissection of the internal mammary pedicle. The essential feature of this technique is the use of Silicone Rubber devices, for the identification and retraction of the internal mammary pedicle during its preparation.

Computerized interactive morphometry of brushing cytology specimens.

Forty-two bronchial brushing cytology specimens were evaluated by a video-based computerized interactive morphometry (CIM) system with an interactive peripheral consisting of a touch-sensitive screen mounted over a high-resolution video monitor. The system was programmed to allow a trained observer to rapidly measure nuclear and cytoplasmic profile diameters of randomly selected cells and to calculate their nuclear-cytoplasmic ratios. The specimens included 13 cytologic slides with no malignant cells present, 14 with non-small cell carcinoma cells and 15 with small cell carcinoma cells.