The effects of varying volumes of crystalloid administration before cesarean delivery on maternal hemodynamics and colloid osmotic pressure.

The value of intravenous crystalloid administration in preventing spinal-induced hypotension in the parturient has recently been questioned. Also, the association between increasing crystalloid volume and decreasing postpartum colloid osmotic pressure (COP) raises concern regarding the risk of maternal and fetal pulmonary edema. To study the dose-response effect of varying amounts of crystalloid volume prior to spinal anesthesia, we measured maternal hemodynamic variables and maternal and fetal COP in three groups of healthy parturients receiving spinal anesthesia for elective cesarean delivery.

Maternal and fetal colloid osmotic pressure following fluid expansion during cesarean section.

Objectives: To characterize the changes in colloid osmotic pressure during delivery and to determine the relationship between maternal and fetal colloid osmotic pressures.

Design: Clinical, prospective study.

Setting: Obstetrical operating theater in a tertiary care university hospital.

Perioperative analgesia with subarachnoid sufentanil administration.

Background And Objectives: Thirty-seven ASA Physical Status I parturients undergoing elective cesarean delivery were evaluated to determine the effects of subarachnoid sufentanil administration.

Methods: This study was carried out in a randomized, double-blind fashion. All patients received 1.

Treatment of donor T cell-mediated hematopoietic suppression after haploidentical bone marrow transplantation by T cell modulation in a patient with severe combined immunodeficiency.

An 8-month-old male patient with severe combined immunodeficiency syndrome was transplanted with maternal, haploidentical T cell-depleted bone marrow without prior conditioning therapy. Acute graft-versus-host disease developed 2 weeks post bone marrow transplantation (BMT) and was successfully treated with cortisone. After cortisone withdrawal the patient developed myeloid and B cell depression concomitant with T cell activation.

Vertebral column length and spread of hyperbaric subarachnoid bupivacaine in the term parturient.

Patient height is considered an important determinant of the dose of spinal anesthesia. However, the relationship between body height and the level of sensory anesthesia with a fixed dose of spinal anesthetic has not been clearly documented. Recent evidence suggests no correlation between height or weight of parturients and spread of spinal anesthesia.

Flumazenil reverses sedation after midazolam-induced general anesthesia in ambulatory surgery patients.

Flumazenil, a specific competitive benzodiazepine antagonist, was evaluated for reversal of residual sedation after midazolam-induced ambulatory general anesthesia. Endotracheal anesthesia was begun with midazolam (mean +/- SD dose 12.4 +/- 2.

High efficiency of a new immunological magnetic cell sorting method for T cell depletion of human bone marrow.

Fresh human bone marrow (BM) mononuclear cells containing a mean of 11% T cells underwent T cell depletion utilizing a newly developed magnetic cell sorter. In order to remove T cells, 10(8) cells were labeled with either a specific CD3 monoclonal antibody or a cocktail of monoclonal CD2 + CD5 + CD7 antibodies and biotin-conjugated magnetic microparticles (size 100-150 nm) employing a streptavidin-FITC complex. Labeled cells were removed by using columns filled with a ferromagnetic matrix and placed within a recess in a strong permanent magnet.

Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia.

The anti-leukemia potential of natural killer (NK) cells has been evaluated in 40 patients transplanted for chronic myelogenous leukemia (CML) to determine whether differences in NK cell function were correlated with subsequent leukemic relapse. Cells from patients and their donors were tested in 51Cr release assays against fully allogeneic CML targets and against cultured K562 targets; cells from 26 patients were tested against host-derived CML targets that were cryopreserved before transplantation. Cultured CML targets (K562) were highly susceptible to lysis by freshly isolated peripheral blood lymphocytes (PBL) and to a greater degree by PBL cultured in medium containing interleukin-2 (IL-2) in all assays performed.

Maternal and fetal catecholamines and uterine incision-to-delivery interval during elective cesarean.

The fetal sympathoadrenal system is activated during periods of intrauterine stress such as inadequate uterine perfusion. During cesarean, the period of interruption of utero-placental blood flow is extended as the time interval from uterine incision to delivery increases. An increasing uterine incision-to-delivery interval with spinal or general anesthesia has been associated with a poorer neonatal outcome.

Comparative effects of subarachnoid hyperbaric bupivacaine and tetracaine-procaine for cesarean delivery.

Hyperbaric solutions of 0.75% bupivacaine (8.25% dextrose), and 1% tetracaine mixed with an equal volume of 10% procaine were compared in a double-blind study of 22 parturients undergoing elective cesarean delivery and spinal anesthesia.

Perioperative analgesia with subarachnoid fentanyl-bupivacaine for cesarean delivery.

Addition of fentanyl to bupivacaine administered for spinal anesthesia for cesarean delivery was evaluated in 56 ASA physical status 1 term parturients. Preservative-free saline was added to 0, 2.5, 5, 6.

Interleukin 2-activated killer cells in patients following transplants of soybean lectin-separated and E rosette-depleted bone marrow.

During the early period following bone marrow transplantation before the immune system has reached full functional maturity, unprimed, nonspecific lytic systems may play a critical role as antiviral or antitumor effectors. The reconstitution of cells with this potential is of particular importance in recipients of bone marrow that has been depleted of mature T lymphocytes to prevent graft v host disease (GVHD). We examined the recovery of natural killer (NK) cells and interleukin 2 (IL 2)-augmented lymphokine-activated killer cells (LAK) in 48 patients at various intervals following transplantation of bone marrow depleted of mature cellular elements by treatment with soybean agglutinin and sheep RBCs (SBA-E- BMT).

[Ambulatory psychotherapy of sex offenses].

We present the theoretical basis and results of a comprehensive research project concerning the psychotherapeutic treatment of sexual offenders in an ambulant setting. The therapeutic sample (n = 86) consists of patients with the following symptoms: exhibitionism, child molestation and sexual aggressive acts towards women. Data concerning the sexual deviant symptomatology, the general and sexual socialization and the actual psycho-social situation are demonstrated.

Cellular immune reactivity to nuclear antigens in systemic lupus erythematosus.

The leucocyte migration test (LMT) was used for the study of cellular responsiveness to nuclear factors, i. e. to calf thymus desoxyribonucleic acid (DNA), calf thymus desoxyribonucleoprotein (DNP), calf liver ribonucleic acid (RNA), in 20 subjects with SLE and in 20 non-immunopathological cases serving as controls.