Publications by authors named "Hau Man Yeung"
Article Synopsis
- Recent studies suggest that adolescent idiopathic scoliosis (AIS) has a multifactorial genetic basis, but the specific heritability has not been thoroughly researched.
- A genetic epidemiology study involving 415 Chinese female patients and their first-degree relatives found a 17.7% recurrence risk of scoliosis among siblings, with higher rates for female siblings.
- The study estimated the heritability of AIS to be 87.5%, reinforcing the idea of a strong genetic influence on the condition and marking a significant contribution to understanding its genetic factors in the Asian population.
Composition vector method based on maximum entropy principle for sequence comparison.
IEEE/ACM Trans Comput Biol Bioinform
April 2014
The composition vector (CV) method is an alignment-free method for sequence comparison. Because of its simplicity when compared with multiple sequence alignment methods, the method has been widely discussed lately; and some formulas based on probabilistic models, like Hao’s and Yu’s formulas, have been proposed. In this paper, we improve these formulas by using the entropy principle which can quantify the nonrandomness occurrence of patterns in the sequences.
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