Publications by authors named "Hatim Almutairi"

Background: Incidence and outcomes of acute kidney injury (AKI) among neonates who underwent open-heart surgery are not well highlighted in the literature. We aim to assess the incidence, risk factors, and outcome of AKI among neonates undergoing open-heart surgery.

Methods: This is a retrospective cohort study between 2016 and 2021 for all neonates requiring open heart surgery.

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EBV latent membrane protein 1 (LMP-1) is an important oncogene involved in the induction and maintenance of EBV infection and the activation of several cell survival and proliferative pathways. The genetic diversity of LMP-1 has an important role in immunogenicity and tumorigenicity allowing escape from host cell immunity and more metastatic potential of LMP-1 variants. This study explored the evolutionary of LMP-1 in EBV-infected patients at an advanced stage of nasopharyngeal carcinoma (NPC).

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Background: Dengue virus (DENV) infection is a global economic and public health concern, particularly in tropical and subtropical countries where it is endemic. Saudi Arabia has seen an increase in DENV infections, especially in the western and southwestern regions. This study aims to investigate the genetic variants of DENV-2 that were circulating during a serious outbreak in Jazan region in 2019.

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Leishmania (Mundinia) procaviensis is a parasitic kinetoplastid that was first isolated from a rock hyrax in Namibia in 1975. We present the complete genome sequence of Leishmania (Mundinia) procaviensis isolate 253, strain LV425, sequenced using combined short- and long-read technologies. This genome will contribute to our understanding of hyraxes as a reservoir.

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Anthroponotic cutaneous leishmaniais (ACL) and zoonotic cutaneous leishmaniasis (ZCL) caused by and , respectively, are endemic vector-borne diseases in southern Saudi Arabia. In 2021, an outbreak of cutaneous leishmaniasis occurred in the province of Asir. The main objective of our investigation was to analyze the epidemiological features of CL in southern Saudi Arabia.

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The conventional morphological characterization of mosquito species remains heavily used for species identification in Jazan, Saudi Arabia. It requires substantial expertise and time, as well as having difficulty in confirming identity of morphologically similar species. Therefore, to establish a reliable and accurate identification system that can be applied to understanding spatial distribution of local mosquito species from the Jazan region, DNA barcoding was explored as an integrated tool for mosquito species identification.

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Porcisia hertigi is a parasitic kinetoplastid first isolated from porcupines (Coendou rothschildi) in central Panama in 1965. We present the complete genome sequence of , isolate C119, strain LV43, sequenced using combined short- and long-read technologies. This complete genome sequence will contribute to our knowledge of the parasitic genus .

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() sp. Ghana is a kinetoplastid parasite isolated in 2015 in Ghana. We report the complete genome sequence of () sp.

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Leishmania (Mundinia) orientalis is a kinetoplastid parasite first isolated in 2014 in Thailand. We report the complete genome sequence of () , sequenced using combined short-read and long-read technologies. This will facilitate greater understanding of this novel pathogen and its relationship to other members of the subgenus .

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Leishmania (Mundinia) enriettii is a parasitic kinetoplastid first isolated from a guinea pig in Brazil in 1946. We present the complete genome sequence of () , isolate CUR178, strain LV763, sequenced using combined short-read and long-read technologies. This will facilitate a greater understanding of the genome diversity within () .

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Article Synopsis
  • The text discusses the genome sequencing data of six Leishmania parasites and one related species, collected from various locations like Thailand, Brazil, and Panama.
  • It explains the process of assembling the genome using Nanopore long reads, followed by correcting errors with Illumina short reads, ensuring high-quality data.
  • The data has been made publicly available through multiple platforms, including NCBI and university archives, and will aid in comparative genomics and parasitology research.
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Article Synopsis
  • The LGAAP computational pipeline efficiently assembled six genomes of a parasite subfamily to chromosome-scale quality using both long- and short-read sequencing data.
  • It is an open-source tool, meaning anyone can access and use it for their research.
  • The pipeline is versatile and can be adapted for assembling other genomes of similar sizes, around 35 megabases.
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Article Synopsis
  • - Leishmania (Mundinia) martiniquensis is a type of parasite that was discovered in 1995 in Martinique.
  • - The first complete genome of this parasite from Asia, specifically the LSCM1 strain LV760, has been sequenced using a mix of short-read and long-read technologies.
  • - This genomic information will help researchers better understand how this subgenus has evolved across different regions.
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Introduction: Heart failure (HF) affects about 320,000 Saudi individuals and is associated with a considerable negative impact on the patients' quality of life. In literature, there is a lack of data about the echocardiographic abnormalities of HF patients in Saudi Arabia.

Aim Of Work: To describe the echocardiographic findings of HF patients in Western Saudi Arabia.

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