Publications by authors named "Hatice Kızıltas"

1,3-Diheterocycloalkanes derivatives are important starting materials in fine organic synthesis. These compounds can be widely used in various fields such as industry, medicine, biotechnology and chemical technology. The paper is focused on synthesis and study of alkoxymethyl derivatives of diheterocycloalkanes (M1-M15) and inhibition effect on carbonic anhydrase and acetylcholinesterase.

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Article Synopsis
  • Onion is rich in dietary components like phenolics and flavonoids, with spiraeoside being a notable flavonoid investigated for its antioxidant properties.
  • Various antioxidant techniques revealed spiraeoside's effectiveness in scavenging radicals, showing results similar to BHT but less potent than standard antioxidants like α-tocopherol and trolox.
  • Additionally, spiraeoside demonstrated significant inhibitory effects on metabolic enzymes linked to diseases such as Alzheimer's, diabetes, and glaucoma, indicating its potential as a therapeutic agent.
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Propolis is a complex natural compound that honeybees obtain from plants and contributes to hive safety. It is rich in phenolic and flavonoid compounds, which contain antioxidant, antimicrobial, and anticancer properties. In this study, the chemical composition and antioxidant activities of propolis were investigated; ABTS, DPPH and DMPD were prepared using radical scavenging antioxidant methods.

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Studies have shown an inverse correlation among age-related illnesses like coronary heart disease and cancer and intake of fruit and vegetable. Given the probable health benefits of natural antioxidants from plants, research on them has increased. is consumed as a food and traditional medicine plant in some regions of Turkey, so evaluation of the biological ability of this species is important.

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Article Synopsis
  • Magnofluorine, a plant-derived secondary metabolite, demonstrates significant antioxidant activity through various bioanalytical assays, outperforming some common synthetic antioxidants.
  • The compound exhibits inhibition effects on key metabolic enzymes associated with diseases like diabetes and Alzheimer's, suggesting potential therapeutic applications.
  • Molecular docking studies indicate Magnofluorine's interactions with these enzymes, highlighting its promise for future industrial and medicinal use.
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In this study, anticholinergic, antidiabetic, antioxidant and cytotoxic activities of L. () were determined. Ethanol extracts of (EERL) and water extract of (WERL) were prepared for biochemical analysis.

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In order to evaluate the antioxidant activity of evaporated ethanolic extract (EESB) and lyophilized water extract (WESB) of Shaggy bindweed ( Mill. Subs), some putative antioxidant methods such as DPPH· scavenging activity, ABTS scavenging effect, ferric ions (Fe) reduction method, cupric ions (Cu) reducing capacity, and ferrous ions (Fe) binding activities were separately performed. Also, ascorbic acid, α-tocopherol and BHT were used as the standard compounds.

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Kınkor () is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this medicinal plant. In this study, the phytochemical composition; some metabolic enzyme inhibition; and antidiabetic, anticholinergic, and antioxidant activities of this plant were assessed.

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The present study was designed to assess the phytochemical content of Ferulago angulata (FA) and possible in vivo nephroprotective effect of FA administration on trace elements, minerals, MDA and GSH in kidney and liver tissue samples, serum vitamin (α-tocopherol, retinol, cholecalciferol, phylloquinone), TSA, and LSA in a rat model of DMN-induced nephrotoxicity. In the study, Wistar albino rats were assigned to six groups: Control (0.9% NaCl), (DMN 10 mg/kg), (FA 150 mg/kg), (DMN + FA 150 mg/kg), (FA 300 mg/kg), and (DMN + FA 300 mg/kg).

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Context: Ferulago angulata (Schlecht.) Boiss. (Apiaceae) (FASB) is used to treat liver diseases and has been used both as food and therapeutics by many cultures for thousands of years because of the natural antioxidant compounds.

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The purpose of this study was to determine the antioxidant and antiradical activities in methanol extracts of two edible mushrooms from Turkey, Agaricus urinascens (Jul. Schäff. & F.

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The purpose of this study was to examine the status of trace elements (Cu, Zn, and Fe) and minerals (Mg, K, Na, and Cl) and the level of biochemical parameters (urea, creatinine, total protein, albumin, and glucose) in hemodialysis (HD) patients. This study included 30 HD patients (25 men and 5 women) aged 52.12 +/- 3.

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