[Role and effectiveness of radioactive-iodine therapy for the treatment of Grave's disease].

The treatment of Graves' disease is based on three therapies: medical treatment with synthetic antithyroid agents, surgery and radioactive-iodine therapy. The purpose of our study was to study the role and effectiveness of radioactive-iodine therapy for the treatment of Graves' disease. We conducted a retrospective, descriptive study of the epidemiological, clinical, paralclinical and therapeutic features of 54 patients with Graves' disease managed and treated with iodine-131 as well as of their short- and medium-term remission rate.

Tektrotyd Scan Showing a Diffuse Bone Metastasis in Patient with a Neuroendocrine Pancreatic Tumor.

A 65-year-old woman presented with a neuroendocrine pancreatic head tumor and known liver and bone metastasis. We performed Tc-99m-tektrotyd scintigraphy on this patient, which showed more developed diffuse bone metastases, in addition to the known lesions.

Pitfall of I-131 whole body scan: a mucinous adenocarcinoma of the ovary.

False positive radioiodine uptake following thyroidectomy for differentiated thyroid cancer has been reported in some cases. A 57-year-old female patient was referred for ablative radioiodine treatment four weeks after undergoing total thyroidectomy for papillary thyroid carcinoma. Posttherapeutic I-131 scintigraphy showed uptake in the neck and large focus in the lower abdomen and pelvis.

Unsual bone metastasis to the rib and the tibia of a follicular variant of papillary thyroid carcinoma.

Usually differentiated thyroid cancer is a slow growing tumor with low metastatic potential. We present the case of female patient of 26-years-old who underwent thyroidectomy, followed by 3.7 GBq of 131 I.

Pulmonary calcification in renal failure patient incidentally revealed by bone scintigraphy.

Pulmonary calcification is a subdiagnosed metabolic lung disease that is commonly asymptomatic and frequently associated with end-stage renal disease. We report a case of a 21-year-old man with a 4-year history of end-stage renal disease without respiratory symptoms. We discover incidentally on a bone scan a pulmonary calcification.

Reflex sympathetic dystrophy syndrome in a child.

Reflex sympathetic dystrophy syndrome (RSDS) is a painful condition that usually follows regional trauma. We report the case of a 13-year-old girl that was seen for a painful swelling of the right hand associated with palmar hyperhidrosis, which occurred after a trauma to the hand. Bone scan images showed early tissue abnormality, which was more significant on the right hand and wrist, as well as moderate bone uptake on the right side.

[Treatment of painful bony metastases with Samarium 153-EDTMP in prostate carcinoma].

Unlabelled: THE OBJECTIVE of this work is to evaluate a new therapy, the metabolic radiotherapy to the 153Samarium-EDTMP, of recent introduction in Tunisia, in the painful bony metastasis treatment observed at the patients affected of cancer of the prostate.

Methods: It is about a retrospective survey with a receding of 40 months, achieved through 45 files of patients having benefited all of this new treatment for painful bony metastases in relation with a prostatic adenocarcinoma and collected by three centers of Nuclear Medicine of the capital: the institute Salah Azaiez (state-controlled), the Center CERU (deprives) and the Military hospital (HMPIT).

Results: We tried to appreciate essentially four parameters: the therapeutic efficiency, the factors influencing the answer in the treatment, the toxicity of the treatment and the sources of failure.

[Scintigraphic preoperative localization of abnormal parathyroid gland].

Unlabelled: THE AIM of this study is to evaluate the accuracy of scintigraphic preoperative localization of abnormal parathyroid gland.

Methods: 25 patients with confirmed hyperparathyroidism undergone scintigraphic and ultrasound localization prior to surgery. Paratthyroid scintigraphy was done with thallium - techetium substraction and technetium-tetrofosmin dual phase techniques.

[Thyroglobulin: usefulness and limits in monitoring patients with thyroid carcinoma].

Unlabelled: The aim of this study was to assess the role of thyroglobulin in monitoring patients with differentiated thyroid carcinoma.

Methods: We retrospectively sudied thirty patients who had total thyroidectomy and had been followed beteween 1999 and 2004 in nuclear medicine department. They have had iodine 131 whole body scans, repeated determination of thyroglobulin, thyreostimulin and thyroglobulin antibodies.

[Metaiodobenzylguanidine scintigraphy in the diagnosis and followup of neuroblastoma. Apropos of 16 cases].

Aims: The aim of this study is to evaluate meta-iodo-benzyl-guanidine scintigraphy in the diagnosis and the management of neuroblastoma.

Patients And Methods: betwen september 1999 and jun 2004, 16 children aging from 4 months to 6 years, with neuroblastoma, underwent mIBG scintigraphy in military hospital nuclear medicine department.

Results: 23 mIBG scans were done.

[Myocardial perfusion scintigraphy].

The aim of this review was to recall the relevance of the myocardial perfusion scintigraphy procedure in the diagnosis of coronary artery disease. Myocardial perfusion scintigraphy is undergone after treadmill exercise or pharmacological stress by infusion of Dipyridamole. Thallium-201, sestamibi-Tc99m and tetrofosmine-Tc99m are the most frequently used tracers.