Publications by authors named "Hasti Khoshamadi"
A Nonlinear State Observer for the Bi-Hormonal Intraperitoneal Artificial Pancreas.
Annu Int Conf IEEE Eng Med Biol Soc
July 2022
Article Synopsis
- Continuous glucose monitoring sensors are crucial for managing blood glucose levels in artificial pancreases, but real-time measurement of insulin and glucagon is currently limited, which affects decision-making.
- The paper proposes a nonlinear high-gain observer designed for a bi-hormonal artificial pancreas to estimate unmeasurable states, using a modified intraperitoneal animal model, accommodating for measurement noise and uncertainties.
- The developed observer is tested in scenarios with hormone infusions and shows promising results, indicating its potential for enhancing the performance of closed-loop systems in managing Type 1 diabetes by better predicting the body's response to hormone treatments.