Publications by authors named "Hassene Rahmani"
Purpose: The aim of this study was to compare the effect of a pressure-controlled strategy allowing non-synchronised unassisted spontaneous ventilation (PC-SV) to a conventional volume assist-control strategy (ACV) on the outcome of patients with acute respiratory distress syndrome (ARDS).
Methods: Open-label randomised clinical trial in 22 intensive care units (ICU) in France. Seven hundred adults with moderate or severe ARDS (PaO/FiO < 200 mmHg) were enrolled from February 2013 to October 2018.
Background: Respiratory mechanics is a key element to monitor mechanically ventilated patients and guide ventilator settings. Besides the usual basic assessments, some more complex explorations may allow to better characterize patients' respiratory mechanics and individualize ventilation strategies. These advanced respiratory mechanics assessments including esophageal pressure measurements and complete airway closure detection may be particularly relevant in critically ill obese patients.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses a study aimed at evaluating non-invasive oxygenation treatments for ICU patients with acute respiratory failure who have do-not-intubate orders, focusing on quality of life and discomfort, not just survival.
- It outlines a multicentre observational study comparing different oxygenation strategies: high-flow nasal oxygen therapy (HFOT), NIV switching with HFOT, and NIV with standard oxygen, with a goal to include at least 330 patients.
- The study has received ethical approval, will involve informed consent from participants, and aims to publish findings in peer-reviewed journals with trial registration number NCT03673631.
Extracorporeal life support in the treatment of colchicine poisoning.
Clin Toxicol (Phila)
November 2015
Context: Ingestions of Colchicum autumnale may lead to severe poisoning. It begins with gastrointestinal symptoms and leukocytosis, followed by multi-organ failure with shock and a possible late recovery phase. Mortality is highly dependent on the ingested dose.
View Article and Find Full Text PDFObjective: To evaluate the efficacy and safety of a step-by-step fixed dose of specific immunotherapy protocol in case of severe digoxin poisoning in an open uncontrolled prospective study.
Methods: Twenty consecutive patients were admitted because of severe digoxin poisoning. The inclusion criteria were: digoxin overdose and either life-threatening arrhythmia; high-degree atrioventricular block, ventricular arrhythmia, or bradycardia less than 50 bpm and hyperkalaemia (>5.