Deciphering community-level knowledge of obstetric fistula and determinants: perspectives elucidated by ordinal logistic regression.

Background: Obstetric fistula is a significant cause of maternal morbidity in resource-limited settings, where women often suffer due to a lack of prompt access to skilled obstetric services. It is imperative to comprehend and identify the factors that shape community knowledge about obstetric fistula to enhance prevention strategies, enable early detection, and provide support and treatment to affected women. However, there is a substantial gap in the available evidence concerning the level of community knowledge regarding obstetric fistula and its influencing factors within the Ethiopian context.

Integrating human biomonitoring exposure data into a primary care morbidity database: a feasibility study.

Background: The detection of a local per- and polyfluoroalkyl substances (PFAS) pollution hotspot in Zwijndrecht (Belgium) necessitated immediate action to address health concerns of the local community. Several human biomonitoring (HBM) studies were initiated, gathering cross-sectional exposure data from more than 10,000 participants. The linkage of these HBM data with primary care health registries might be a useful new tool in environmental health analysis.

Magnitude of telemedicine utilization and associated factors among health professionals working at selected public hospitals in Southern Ethiopia.

Background: Despite the immense potential of telemedicine, its implementation in Ethiopia and other developing nations has faced formidable challenges, leading to disappointingly low utilization rates. Therefore, this study sought to assess the magnitude and factors associated with telemedicine service practice among healthcare professionals in the pilot public hospitals of Sidama and Southern Nations Nationalities Peoples Regions.

Methods: Cross-sectional study was conducted from June 1-30, 2021 among randomly selected 407 health professionals working at Pilot Hospitals in Southern Ethiopia.

Association of environmental pollutants with asthma and allergy, and the mediating role of oxidative stress and immune markers in adolescents.

Background: Asthma and allergic diseases are among the common causes of morbidity and mortality globally. Various environmental pollutants are linked to the development of asthma and allergic diseases. Evidence on the role of oxidative stress and immune markers in the association of environmental pollutants with asthma and allergy is scant.

Mental health issues and the association of mental health literacy among adolescents in urban Ethiopia.

Background: Epidemiological evidence about the prevalence of adolescent mental health issues and their association with mental health literacy is crucial for sustained mental health promotion strategies. Adolescence is a critical life stage for mental health promotion. However, evidence is not available among Ethiopian school adolescents.

A narrative review on problems in product quality, regulatory system constraints, and the concept of quality by design as a solution for quality assurance of African medicines.

Background: The provision of medicines with confirmed quality and efficacy is critical for maintaining the public health and building confidence in the healthcare systems. However, the presence of poor-quality medicines still presents a significant challenge in the pharmaceutical landscape across the African regions. This is further exacerbated by the lack of consistency or discrepancy in the current regulatory framework.

MeSH2Matrix: combining MeSH keywords and machine learning for biomedical relation classification based on PubMed.

Biomedical relation classification has been significantly improved by the application of advanced machine learning techniques on the raw texts of scholarly publications. Despite this improvement, the reliance on large chunks of raw text makes these algorithms suffer in terms of generalization, precision, and reliability. The use of the distinctive characteristics of bibliographic metadata can prove effective in achieving better performance for this challenging task.

Trends and disparities in ever-breastfeeding practice and early breastfeeding initiation in Ethiopia: a 20-year trend analysis from EDHS datasets.

Background: Ethiopia has had a long-standing national commitment to improving child health for the last five decades. However, evidence on trends of ever-breastfeeding and early initiation remained fragmented, and there existed a paucity of holistic evidence on the extent of the impacts of the policy and the associated factors. This study examined trends, disparities, and factors influencing ever-breastfed and early initiation in the last twenty years.

Green synthesis and characterization of magnetite nanoparticles using Eucalyptus globulus leaves for water treatment and agronomic valorization.

This work presents a new process, based on the green nanoparticles FeO and magnetization coupling for the treatment of saline well water. In this context, iron nanoparticles were synthesized using Eucalyptus globulus leaves. The nanomaterials were characterized by scanning electron microscopy and infrared for identification.

Acute Effects of Caffeine Ingestion on Postural Balance, Functional Capacity and Cognitive Function in Patients with End Stage Renal Disease.

Patients with end stage renal disease (ESRD) display many cognitive and physiological alterations resulting from renal failure and physical inactivity. Caffeine intake has been reported to improve cognitive/physical performance in several studies. However, whether the benefits of caffeine intake apply to patients with ESRD remains unknown.

Deciphering temporal perspectives: A key to happiness and optimism for healthy aging in nursing practices".

Background: With the global population of older individuals increasing rapidly, it is important to understand the factors contributing to their well-being. The study aimed to investigate the relationship between older adults' time perspective and their experiences of happiness and optimism.

Methods: A cross-sectional survey was conducted on a substantial sample size of 300 older adults from January to March 2023.

Effect of Diets with the Addition of Edible Insects on the Development of Atherosclerotic Lesions in ApoE/LDLR Mice.

Foods enriched with insects can potentially prevent several health disorders, including cardiovascular diseases, by reducing inflammation and improving antioxidant status. In this study, and were selected to determine the effect on the development of atherosclerosis in ApoE/LDLR mice. Animals were fed AIN-93G-based diets (control) with 10% (TM) and 10% (GA) for 8 weeks.

Survival Patterns Among Patients With Breast Cancer in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.

Importance: Breast cancer is the most prevalent cancer globally with tremendous disparities both within specific regions and across different contexts. The survival pattern of patients with breast cancer remains poorly understood in sub-Saharan African (SSA) countries.

Objective: To investigate the survival patterns of patients with breast cancer in SSA countries and compare the variation across countries and over time.

Nexus between postpartum depression and exclusive breastfeeding practices among lactating mothers in Assosa Town, West Ethiopia.

Background: Across the globe, breastfeeding stands out as a highly effective strategy for reducing infant and child morbidity and mortality. Concurrently, postpartum depression (PPD) emerges as a notable public health issue, adversely affecting both exclusive breastfeeding (EBF) practices for infants and the fulfillment of parenting roles. Despite the lack of substantial evidence in Ethiopia and the specific study areas, indicating the association between PPD and EBF practices, this study endeavors to fill this gap.

Blunted cerebral hemodynamic responses to incremental exercise in patients with end-stage renal disease.

Purpose: The aims of this study were to compare cerebral hemodynamics and maximal oxygen uptake (VO) in patients with end-stage renal disease (ESRD) vs. age-matched healthy controls during maximal exercise.

Methods: Twelve patients with ESRD and twelve healthy adults (CTR group) performed exhaustive incremental exercise test.

Development and validation of a simplified risk prediction model for preterm birth: a prospective cohort study in rural Ethiopia.

Preterm birth is one of the most common obstetric complications in low- and middle-income countries, where access to advanced diagnostic tests and imaging is limited. Therefore, we developed and validated a simplified risk prediction tool to predict preterm birth based on easily applicable and routinely collected characteristics of pregnant women in the primary care setting. We used a logistic regression model to develop a model based on the data collected from 481 pregnant women.

Hemodynamic and neuromuscular basis of reduced exercise capacity in patients with end-stage renal disease.

Purpose: The present study aimed to characterize the exercise-induced neuromuscular fatigue and its possible links with cerebral and muscular oxygen supply and utilization to provide mechanistic insights into the reduced exercise capacity characterizing patients with end-stage renal disease (ESRD).

Methods: Thirteen patients with ESRD and thirteen healthy males (CTR group) performed a constant-force sustained isometric contraction at 50% of their maximal voluntary isometric contraction (MVC) until exhaustion. Quadriceps muscle activation during exercise was estimated from vastus lateralis, vastus medialis, and rectus femoris EMG.

Performance of mid-upper arm circumference to identify adolescents with obesity and metabolic syndrome: NHANES 2011-2018 analysis.

Background: Mid-upper arm circumference (MUAC) was recommended for screening of adolescents with obesity, although its diagnostic performance with respect to high-precision assessment of body composition remains unknown.

Objective: To evaluate the diagnostic performance of MUAC in identifying obesity and metabolic syndrome in U.S.

Substandard and falsified antimicrobials in selected east African countries: A systematic review.

Background: Globally, millions of people have been affected by fraudulent pharmaceutical products, particularly those in developing countries. Although the problem of falsified and substandard drugs is acknowledged, the extent of the issue is ever-changing, has a dynamic nature, and should be quantified and captured in a recent snapshot.

Objective: This systematic review seeks to examine the data that can quantify and provide a current snapshot of the prevalence of SF antimicrobials in selected east Africa countries.

Disparities in the non-laboratory INTERHEART risk score and its components in selected countries of Europe and sub-Saharan Africa: analysis from the SPICES multi-country project.

Aims: Accurate prediction of a person's risk of cardiovascular disease (CVD) is vital to initiate appropriate intervention. The non-laboratory INTERHEART risk score (NL-IHRS) is among the tools to estimate future risk of CVD. However, measurement disparities of the tool across contexts are not well documented.

Selected food items adulteration, their impacts on public health, and detection methods: A review.

Every living thing requires food to survive. Clean, fresh, and healthy foods are important to human health. Today, food is affected by various counterfeits.

A Bioinformatic Study on the Potential Anti-Vitiligo Activity of a Compound.

The plant has traditionally been known for its wide applications in diseases, especially vitiligo, which is characterized by patches and white macules caused by the loss of melanocytes. One of the chemical treatments for vitiligo consists mainly of skin repigmentation and usually leads to a non-durable effect by inhibiting the Janus kinase (JAK) signal transduction (STAT pathway). JAK inhibitors generally block multiple JAK tyrosine kinases, which leads to secondary effects.

Association between long-term weight loss and obesity-related complications defined by Edmonton obesity staging system: analysis from the NHANES (2011-2018).

Background/objective: A successful Long-Term Weight Loss (LTWL) is associated with a more favorable metabolic disease risk profile. However, evidence is limited on the association of LTWL with obesity-related complications defined by Edmonton obesity staging system (EOSS). Hence, our study aims to assess the association between LTWL thresholds and obesity-related complications defined by EOSS among the adult US population.

[Socio-demographic and clinical profile of a population of patients coming for consultation to the psychiatric department of a general hospital in southern Tunisia].

Introduction: mental disorders are a very common health condition and a major public health issue. The purpose of this study was to examine the epidemiological and clinical characteristics of patients coming for consultation to the psychiatric department of the Regional Hospital of Gabes, and to identify risk factors for the main mental disorders.

Methods: we conducted a retrospective study, including all patients consulting the psychiatry department of Gabes for the first time between 01/01/2010 and 31/12/2013.