Publications by authors named "Hassana Kyari Mangga"
Article Synopsis
- Contagious ecthyma, or Orf, is a significant zoonotic disease impacting ruminants, posing economic challenges due to its effects on animal health and trade.
- A study infected lamb testicle cells with a scab sample from an infected goat, confirming the Orf virus presence through PCR and sequencing its genome, which consists of 132,124 bp.
- The analysis found that the Malaysian ORFV strain UPM/HSN-20 shares 97.3-99.0% similarity with other strains, particularly those from China, providing insights into genetic diversity and potential control strategies for the virus.
Immunomodulatory Strategies for Parapoxvirus: Current Status and Future Approaches for the Development of Vaccines against Orf Virus Infection.
Vaccines (Basel)
November 2021
Orf virus (ORFV), the prototype species of the parapoxvirus genus, is the causative agent of contagious ecthyma, an extremely devastating skin disease of sheep, goats, and humans that causes enormous economic losses in livestock production. ORFV is known for its ability to repeatedly infect both previously infected and vaccinated sheep due to several immunomodulatory genes encoded by the virus that temporarily suppress host immunity. Therefore, the development of novel, safe and effective vaccines against ORFV infection is an important priority.
View Article and Find Full Text PDFContagious ecthyma (CE) is an infectious disease of small ruminants caused by a parapoxvirus of family Poxviridae subfamily Chordopoxvirinae. The disease is obviously distinguished by an establishment of scabby lesions and ulcerative formation on less hairy areas including muzzle, ears, nostril, and sometimes on genitalia. The disease is endemic in sheep and goats.
View Article and Find Full Text PDFAn association of Orf virus infection among sheep and goats with herd health programme in Terengganu state, eastern region of the peninsular Malaysia.
BMC Vet Res
July 2019
Background: Orf virus causes a scabby skin lesions which decreases productivity in small ruminants. The unknown status of this disease in the eastern region of Peninsular Malaysia warrants a study to determine sero-prevalence of orf with regards to farmers' compliance level towards the Herd Health Program (HHP) programme.
Results: Out of 504 animals, 115 were positive for Orf-virus antibodies.