Publications by authors named "Hassan Zare Asl"

Article Synopsis
  • - This study presents a new porous sponge made from sodium alginate and gellan gum, created using a freeze-drying process, which incorporates bromelain in a nanoemulsion for enhanced properties.
  • - The sponge showcases impressive physicochemical characteristics, including high swelling capacity, porosity, and biodegradability, while also demonstrating significant antibacterial and anti-inflammatory qualities effective against pathogens like S. aureus and E. coli.
  • - In both lab tests and animal studies, the sponge proved highly effective in promoting wound healing, achieving a complete closure of full-thickness wounds, indicating its potential for clinical applications in wound care.
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One concern that has been considered potentially fatal is bacterial infection. In addition to the development of biocompatible antibacterial dressings, the screening and combination of new antibiotics effective against antibiotic resistance are crucial. In this study, designing hemostasis electrospun composite nanofibers containing chitosan (CS), polyvinyl pyrrolidone (PVP) and Gelatin (G) as the major components of hydrogel and natural nanofibrillated sodium alginate (SA)/polyvinyl alcohol (PVA) and ZnO nanoparticles (ZnONPs) combination as the nanofiller ingredient, has been investigated which demonstrated significant potential for accelerating wound healing.

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This study constructed bilayer nano-hydrogels using solvent casting and electrospinning techniques. The first layer consisted of a hydrogel containing sodium alginate and gellan gum, while the second layer was a carrageenan/polyvinyl alcohol nanofibrous membrane. The nanohydrogels were prepared with different doses of doxycycline antibiotic (0.

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