Novel interfaces for internet of wearable electrochemical sensors.

The integration of wearable devices, the Internet of Things (IoT), and advanced sensing platforms implies a significant paradigm shift in technological innovations and human interactions. The IoT technology allows continuous monitoring in real time. Thus, Internet of Wearables has made remarkable strides, especially in the field of medical monitoring.

Stem cell activity-coupled suppression of endogenous retrovirus governs adult tissue regeneration.

Mammalian retrotransposons constitute 40% of the genome. During tissue regeneration, adult stem cells coordinately repress retrotransposons and activate lineage genes, but how this coordination is controlled is poorly understood. Here, we observed that dynamic expression of histone methyltransferase SETDB1 (a retrotransposon repressor) closely mirrors stem cell activities in murine skin.

Assessment of quality of life of stroke survivors and their caregivers presenting to a tertiary care hospital in Pakistan.

Objective: To determine the quality of life of stroke survivors and their caregivers presenting to a tertiary care setup.

Methods: The descriptive study was conducted from July to December 2019 at the Neurology Department, Pakistan Institute of Medical Sciences, Islamabad, Pakistan, and comprised patients of either gender with ischaemic or haemorrhagic stroke aged 40-70 years and their caregivers. Data was collected using the stroke-specific quality of life Scale and the caregiver quality of life questionnaire.

The journey from viral hepatitis to hypocythemia: Two case reports.

Acute viral hepatitis, including hepatitis A, B, E, D, and G, can lead to severe bone marrow suppression due to cytotoxic lymphocytes. The bone marrow suppression causes aplastic anaemia which is mostly unresponsive to immunosuppressive therapy. Such patients require bone marrow transplant for a complete cure.

Evolution of codon usage in genomes and its impact on the host.

The beef tapeworm, also known as , is a zoonotic tapeworm from the genus in the order Cyclophyllidea. is a food-borne zoonotic parasite with a worldwide distribution. It poses serious health risks to the host and has a considerable negative socioeconomic impact.

Unpredictability of SARS-CoV-2: Pneumoperitoneum a rare complication.

COVID-19 is a viral disease caused by a novel coronavirus that ignited the ongoing pandemic in December 2019. The infected patients may be asymptomatic, have fever and myalgias, develop mild pulmonary symptoms or go into overt respiratory failure. There is also a significant number of patients with gastrointestinal and thromboembolic disease presentation and complications.

Analysis of codon usage bias of lumpy skin disease virus causing livestock infection.

Lumpy skin disease virus (LSDV) causes lumpy skin disease (LSD) in livestock, which is a double-stranded DNA virus that belongs to the genus of the family . LSDV is an important poxvirus that has spread out far and wide to become distributed worldwide. It poses serious health risks to the host and causes considerable negative socioeconomic impact on farmers financially and on cattle by causing ruminant-related diseases.

Awareness and adherence to lifestyle modifications in hypertensive patients presenting to a tertiary care setting.

Objective: To assess the level of awareness and adherence to lifestyle modifications in hypertensive patients.

Methods: The descriptive study was conducted from January to June 2019 at the Pakistan Institute of Medical Sciences, Islamabad, Pakistan, and comprised adult patients of either gender with hypertension history of at least 1 year. Data was collected using a structured questionnaire to evaluate the subjects' awareness and adherence to lifestyle modifications for the control of hypertension.

The Association of Elevated Serum Lipids with Occurrence and Severity of Diabetic Retinopathy in Type II Diabetics Presenting in a Tertiary Care Hospital.

A descriptive, cross-sectional study, was conducted in the Department of Internal Medicine and Ophthalmology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan, from May to November 2018. The aim was to ascertain the frequency of elevated serum lipids and diabetic retinopathy; and compare the serum lipid levels with severity of diabetic retinopathy among Type II diabetic patients. A total of 262 patients having Type II diabetes aged 35 to 65 years were included.

Enteric Fever: Diagnostic Dilemma Encountered in Domperidone-Induced Neuroleptic Malignant Syndrome.

Enteric fever is a multisystem illness caused by Typhi and Paratyphi, and it is associated with a spectrum of conditions ranging from minor cases of diarrhea and low-grade fever to a potentially fatal illness that can lead to gastrointestinal (GI) perforation, hemorrhage, central nervous system (CNS) involvement. Neuroleptic malignant syndrome (NMS) is predominantly described as an idiosyncratic reaction to neuroleptic medications. However, it has also been associated with a variety of drugs that reduce dopaminergic activity.