Maternal dietary nitrate intake and risk of neural tube defects: A systematic review and dose-response meta-analysis.

Despite growing evidence for the potential teratogenicity of nitrate, knowledge about the dose-response relationship of dietary nitrate intake and risk of specific birth defects such as neural tube defects (NTDs) is limited. Therefore, the aim of this meta-analysis was to synthesize the knowledge about the dose-response relation between maternal dietary nitrate intake and the risk of NTDs. We conducted a systematic search in PubMed, ISI Web of Science and Scopus up to February 2018 for observational studies.

Evaluation of the effect of some additives on the efficiency of binder liquid in wet agglomeration of crystals.

Objective: Wet agglomeration is a process wherein dispersed particles are held together in an aggregated form by the presence of a small quantity of solvent which acts as binder liquid. In this work, the efficiency of binder liquid was tested in the presence of various additives.

Methods: Solid state of carbamazepine (CBZ) agglomerates was characterized by DSC and FT-IR.