Fabrication and antimicrobial properties of novel meropenem-honey encapsulated chitosan nanoparticles against multiresistant and biofilm-forming Staphylococcus aureus as a new antimicrobial agent.

Background: Honey exhibits a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) ones. Chitosan (Cs) is a mucoadhesive polymer that also has antibacterial properties. Special attention has been paid to the design of polymeric nanoparticles (NPs) as new nano drug delivery systems to overcome bacterial resistance and its problems.

Epitope mapping of outer membrane protein W (OmpW) and laboratory study of an OmpW-derivative peptide.

Outer membrane protein W (OmpW) is a less-known antigen with potential immunogenic properties. The epitopes of this protein are not well-identified yet. Therefore, in the present study, B- and T-cell epitopes of OmpW were found using comprehensive in silico and partially in vitro studies.

BoHV-1 affects abortion and progesterone in dairy cows Bovine alphaherpesvirus 1 (BoHV-1) seropositivity, progesterone levels and embryo loss of 30-day-old pregnant dairy cows in Zagros Industrial Dairy Farm in Shahrekord: Examination and analysis.

Background: Bovine alphaherpesvirus 1 (BoHV-1) is a serious disease with severe negative economic effects on the global cattle sector, especially in Iran.

Objective: This cross-sectional study was carried out to examine the seroprevalence and associated risk factors of BoHV-1 infection with progesterone levels and embryo death in 30-day pregnant dairy cattle at Zagros Industrial Dairy Farm in Shahrekord, Iran.

Methods: Between December 2017 to February 2018, blood samples were obtained from 60 dairy cow herds.

Two peptides derivate from Acinetobacter baumannii outer membrane protein K as vaccine candidates: a comprehensive in silico study.

Background: The lack of appropriate vaccines is an obstacle to the effective management of A. baumannii infections. Peptide vaccines offer an attractive and promising preventive strategy against A.

Prevalence of Salmonella Typhimurium and Salmonella Enteritidis isolated from poultry meat: virulence and antimicrobial-resistant genes.

Salmonellosis, a zoonotic disease, is one of the leading causes of foodborne illness worldwide. It is responsible for most infections caused by consumption of contaminated food. In recent years, a significant increase in the resistance of these bacteria to common antibiotics has been observed, posing a serious threat to global public health.

Frequency distribution of virulence factors and antibiotic resistance genes in uropathogenic Proteus species isolated from clinical samples.

One of the most common causes of urinary tract infections (UTIs) is Proteus species. Because there is little information on the pathogenicity of Proteus species isolated from Iran, we assessed their virulence characteristics and antibiotic resistance in this study. In Shahrekord, Iran, 260 isolates of Proteus causing UTIs were identified from patients.

Relationship between Biofilm Formation and Antibiotic Resistance and Adherence Genes in Strains Isolated from Raw Cow Milk in Shahrekord, Iran.

The production of biofilms by contributes significantly to treatment failures. The present study aims to establish the relationship between biofilm formation and antibiotic resistance and adhesion genes in strains isolated from raw cow milk in Shahrekord, Iran. A total of 90 samples of raw cow's milk were collected.

Prevalence, antimicrobial resistance, virulence gene profile and molecular typing of Campylobacter species isolated from poultry meat samples.

Background: Campylobacter jejuni and Campylobacter coli are the most significant Campylobacter species responsible for severe gastrointestinal disorders. Raw poultry meat is considered a source of Campylobacter transmission to the human population.

Objectives: The present study was aimed to assess the prevalence rate, antibiotic resistance properties, virulence characters and molecular typing of C.

Molecular characterization of Enterobacter aerogenes isolated from urinary tract infections in Iran.

The prevalence of multidrug-resistant Enterobacter aerogenes strains in UTIs is increasing. Therefore, the purpose of this study was to examine the mechanisms of resistance in Enterobacter aerogenes strains isolated from the urinary tract of infected patients. To achieve this goal, 786 urine samples from Shahrekord, Iran, were collected from June 2019 to February 2020.

Genotyping, antibiotic resistance and prevalence of Arcobacter species in milk and dairy products.

Background: Arcobacter spp. has been considered an emerging foodborne pathogen and a hazard to human health. The dairy chain has been isolated from different sources; nevertheless, data on Arcobacter occurrence in raw milk and dairy products in Iran are still scant.

Novel NAD-independent Avibacterium paragallinarum: Isolation, characterization and molecular identification in Iran.

Background: Infectious coryza (IC) is an invasive upper respiratory disease caused by Avibacterium paragallinarum that affects birds, particularly chickens. The objective of this study is to isolate, characterize and molecularly identify the bacterium A. paragallinarum in poultry birds, as well as to determine its antibiotic sensitivity and resistance.

Molecular characterization and antimicrobial resistance of Enterococcus faecalis isolated from seafood samples.

Background: Enterococcus faecalis is considered an opportunistic foodborne pathogen. The present study aimed to assess the prevalence, antimicrobial resistance, virulence characters, and molecular typing of E. faecalis strains isolated from seafood samples.

Genotyping of Chlamydia abortus using multiple loci variable number of tandem repeats analysis technique.

Background: The correlation between various factors (geographical region, clinical incidence, and host type) and the genomic heterogeneity has been shown in several bacterial strains including Chlamydia abortus.

Methods: The aim of this study was to survey the predominant types of C. abortus strains isolated from ruminants in Iran by the multiple loci variable number of tandem repeats (VNTR) analysis (MLVA) method.

Prevalence of Virulence Genes and Antibiotic Resistance Pattern in Isolated from Urinary Tract Infection in Shahrekord, Iran.

Background: This study aims to specify the antimicrobial resistance pattern and virulence genes of isolated from urinary tract infections in Shahrekord, Iran.

Methods: Urine samples of 1000 people suspected of having urinary tract infections referred to Shahrekord medical diagnostic laboratories were examined. Biofilm assays were performed by microtiter plate test through reading the OD490.

Insight into population structure of isolates in the multiethnic province of Alborz, Iran.

Background And Objectives: Genetic diversity of clinical isolates from tuberculosis patients in the multiethnic province of Alborz, Iran was assessed.

Materials And Methods: A total of 17 isolates in the period of 2012-2013 were collected and subjected to a Multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) consisted of 6 variable numbers of tandem repeats (VNTRs) including ETR-A, ETR-B, ETR-C, ElTR-D, ETR-E, ETR-F, 5 Mycobacterial Interspersed Repetitive Units including MIRU10, MIRU16, MIRU26, MIRU39, MIRU40, and 1 Queen University of Belfast locus, QUB11.

Results: This classified all isolates into 17 distinct MIRU-VNTR types, a reflection of a highly heterogenic population.

Recognition of (Sesc) for Easy Identification of and Molecular and Phenotypic Study of Β-Lactam Resistance in Isolates in Isfahan.

Background: Not only is it crucial to rapidly detect isolates from a broad range of bacteria, but recognizing resistance agents can greatly improve current diagnostic and therapeutic strategies.

Methods: The current cross-sectional study investigated 120 clinical isolates from a nosocomial infection. The isolates were identified using common biochemical tests, and specific surface protein C () primers were used to confirm the presence of .

Pomegranate peel extract inhibits internalization and replication of the influenza virus: An study.

Objective: Influenza virus, which is associated with high level of morbidity and mortality, has been recently considered a public health concern; however, the methods of choice to control and treat it are limited. Our previous study showed anti-influenza virus activity of pomegranate peel extract (PPE). In this study, the mechanism through which PPE acts against influenza virus A/Puerto Rico/8/34 (H1N1; PR8) was investigated.

Phenotypic and molecular characterization of antimicrobial resistance in Trueperella pyogenes strains isolated from bovine mastitis and metritis.

Background: Trueperella pyogenes is one of the most clinically imperative bacteria responsible for severe cases of mastitis and metritis, particularly in postpartum dairy cows. The bacterium has emergence of antibiotic resistance and virulence characters. The existing research was done to apprise the phenotypic and genotypic evaluation of antibiotic resistance and characterization of virulence factors in the T.

Virulence factors and antibiotic resistance properties of the strains isolated from hospital infections in Ahvaz, Iran.

Background: Resistant strains are considered to be one of the major causes of human clinical infections in hospitals. The present investigation was done to study the pattern of antibiotic resistance and the prevalence of virulence and antibiotic resistance genes amongst the strains isolated from human hospital infections.

Methods: One hundred hospital infectious samples were collected and strains were identified using culture and biochemical tests.

in sheep, goat, and camel raw meat: virulence and antibiotic resistance pattern.

genus belongs to a group of Gram-negative coccobacillus. These bacteria are isolated from human and animal origins. Antimicrobial agents play a vital role in treating infectious diseases in both humans and animals, and in this regard is defined as an organism of low virulence.

Prevalence and phenotypic pattern of antibiotic resistance of Acinetobacter baumannii isolated from different types of raw meat samples in Isfahan, Iran.

Resistant Acinetobacter baumannii isolates are not only known as opportunistic nosocomial bacteria but may also be regarded as emerging bacterial contaminants in foods of animal origins. The present investigation was done to assess the prevalence and antibiotic resistance pattern of A. baumannii isolated from different types of raw meat samples.

Genotyping and distribution of putative virulence factors and antibiotic resistance genes of strains isolated from raw meat.

Background: strains with multiple antimicrobial resistance are primarily known as opportunistic nosocomial bacteria but they may also be regarded as emerging bacterial contaminants of food samples of animal origin. Here we aimed to study the molecular characteristics of the strains isolated from raw meat samples.

Methods: A total of 22 strains were isolated from 126 animal meat samples and were genotyped by ERIC-PCR method and by PCR detection of their virulence and antimicrobial resistance determinants.

The role of zoonotic chlamydial agents in ruminants abortion.

Background And Objectives: Enzootic abortion of ewes (EAE) is caused by infection of sheep and goats by bacterium. Chlamydial abortion in bovine could occur by and is the causative agent of psittacosis or ornithosis disease in humans and birds. It also causes acute pneumonia in cattle and sheep.

Detection and subtyping avian metapneumovirus from turkeys in Iran.

Avian metapneumovirus (aMPV) causes diseases like rhinotracheitis in turkeys, swollen head syndrome in chickens and avian rhinotracheitis in other birds. Causing respiratory problems, aMPV adversely affects production and inflicts immense economic losses and mortalities, especially in turkey flocks. In recent years, several serological and molecular studies have been conducted on this virus, especially in poultry in Asia and Iran.

Occurrence of feline herpesvirus 1 and calcivirus in domestic cats of Iran.

Background And Objectives: and are the main causes of feline upper respiratory tract disease. This study was conducted to identify of FeHV-1, FCV and infections in domestic cat population and also to estimate the prevalence of each specific infection in Iran.

Materials And Methods: The ocular conjunctiva and oropharyngeal specimens obtained from 80 cats were examined using PCR and reverse transcription PCR.