Drug resistance is still a significant barrier to effective hepatocellular carcinoma therapy. Address the issue of doxorubicin resistance and inter-receptor crosstalk various doxorubicin formulations were investigated. Hepatocellular carcinoma was carried out using 3-methylechloroanthrene.
View Article and Find Full Text PDFMaterials (Basel)
January 2024
Chemical shrinkage (CS) is an intrinsic parameter that may affect the early age cracking of paste, mortar and concrete. It is well known as the driving force of self-desiccation, autogenous shrinkage (AGS) and drying shrinkage. During the first stage of cement hydration (at the initial setting time), the CS and AGS are equal.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
February 2023
The main aim of this study is to examine the effect of incorporating limestone fine (LF) on chemical shrinkage of pastes and mortars. For this purpose, five paste and five mortar mixes were prepared with 0, 5, 10, 15, and 20% (by weight) LF as a replacement of cement. The water-to-binder (w/b) ratio was 0.
View Article and Find Full Text PDFObjectives: Type 2 diabetes mellitus (DMT2) is contributed to dual interactions between environmental factors and certain genetic factors. This impressed a great need for novel treatment strategy. Nevertheless, ( as a terrestrial herb is considered to be an important source of natural antioxidants, it could be assessed as an anti-hyperglycemic agent.
View Article and Find Full Text PDFMicrobial fermentation of plant material alters the composition of volatile and non-volatile plant natural products. We investigated the antioxidant, anticancer, and antiviral properties of extracts of defatted soybean meal fermented with Aspergillus fumigatus F-993 or A. awamori FB-133 using in vitro methods.
View Article and Find Full Text PDFNon-alcoholic fatty liver disease is a leading cause of chronic liver disease in western countries. The current study aimed to detect and evaluate lipidomic biomarkers for early detection of NAFLD as well as the potential efficiency of methanolic extract of Eclipta prostrata (E. prostrata) on disease management.
View Article and Find Full Text PDFEgypt has the highest prevalence of hepatitis C virus (HCV) in the world. It has been suggested that not only the virus but also the interaction between the virus and the host immune system is important in determining the course of the infection and the response to interferon (IFN)-based therapy. While the adaptive immune system plays a critical role in HCV infection, the innate immune system has only been recognized recently.
View Article and Find Full Text PDFHemangiomas of the gastrointestinal tract and mesentery are uncommon benign vascular lesions. While spontaneous bleeding is the hallmark of the gastrointestinal tumor variant, clinical signs of mesenteric hemangiomas are mostly unspecific. Despite the increasing imaging quality of computerized tomography (CT), in most cases the final diagnosis is established through surgery and histopathologic analysis of a macrobiopsy.
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